Publications

Publications from the sPARK research community. Filter by lab core papers, member authorship, or topic.

12 publications matching “PDAC

TitleYear

Daraxonrasib in Previously Treated Advanced RAS-Mutated Pancreatic Cancer

Wolpin BM, Park W, Garrido-Laguna I, Spira A, Starodub A, Sommerhalder D, Punekar SR, et al., for the RMC-6236-001 Investigators

N Engl J Med

sPARK LabWungki Park
2026

Pembrolizumab and Olaparib in HRD Metastatic Pancreatic Cancer: The POLAR Trial

Park W (Corresponding Author), O’Reilly E, et al.

Nature Medicine

sPARK LabWungki Park
2026

Setidegrasib in Advanced Non–Small-Cell Lung Cancer and Pancreatic Cancer

Park W, Kasi A, Spira AI, Paz-Ares Rodríguez L, Herzberg BO, Pelster MS, et al.

N Engl J Med

sPARK LabWungki Park
2026

Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival

Varghese AM, Perry MA, Chou JF, Nandakumar S, Muldoon D, Erakky A, … Park W, …

Nature Medicine 31(2), 466–477

sPARK LabWungki Park
2025

RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

Sethna Z, Guasp P, Reiche C, Milighetti M, Ceglia N, Patterson E, Lihm J, …

Nature 639(8056), 1042–1051

sPARK LabWungki Park
2025

Distinct clinical outcomes and biological features of specific KRAS mutants in human pancreatic cancer

McIntyre CA, Grimont A, Park J, Meng Y, Sisso WJ, Seier K, Jang GH, … Park W, …

Cancer Cell 42(9), 1614–1629

sPARK LabWungki Park
2024

Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer

Rojas LA, Sethna Z, Soares KC, Olcese C, Pang N, Patterson E, Lihm J, … Park W, …

Nature 618(7963), 144–150

sPARK LabWungki Park
2023

Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer

Reyngold M, O'Reilly EM, Varghese AM, Fiasconaro M, Zinovoy M, … Park W, …

JAMA Oncology 7(5), 735–738

Wungki Park
2021

Early-onset pancreas cancer: clinical descriptors, genomics, and outcomes

Varghese AM, Singh I, Singh R, Kunte S, Chou JF, Capanu M, Wong W, … Park W, …

JNCI: Journal of the National Cancer Institute 113(9), 1194–1202

Wungki Park
2021

Pancreatic cancer: a review

Park W, Chawla A, O'Reilly EM

JAMA 326(9), 851–862

Wungki Park
2021

Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma

McIntyre CA, Lawrence SA, Richards AL, Chou JF, Wong W, Capanu M, … Park W, …

Cancer 126(17), 3939–3949

sPARK LabWungki Park
2020

Genomic methods identify homologous recombination deficiency in pancreas adenocarcinoma and optimize treatment selection

Park W, Chen J, Chou JF, Varghese AM, Yu KH, Wong W, Capanu M, …

Clinical Cancer Research 26(13), 3239–3247

sPARK LabWungki Park
2020