Publications

Publications from the sPARK research community. Filter by member authorship or year.

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430P CLDN18. 2 and KRAS signaling shape tumor states and immune microenvironment in pancreatic cancer (PC)

V Nasca, M Hilmi, N Tezcan, M Perry, M May, J Song, F Balogun, ...

Annals of Oncology 37, S157

sPARK LabEileen O'ReillyFiyinfolu BalogunWungki Park
2026

Abstract A042: ctDNA KRAS detection in pancreatic ductal adenocarcinoma: Platform concordance, sensitivity and clinical associations in a contemporary cohort

J Guo, M May, MF Berger, E Cismas, M Hilmi, A Singhal, F Balogun, ...

Cancer Research 86 (18_Supplement_2), A042-A042

sPARK LabEileen O'ReillyFiyinfolu BalogunWungki Park
2026

Brain metastasis from KRAS wild-type pancreatic cancer and organoid correlates: a case report

Kouassi FM, Patel H, Karnoub ER, Tsang CF, Hohenleitner J, Basturk O, Budagavi D, Moza M, et al.

J Gastrointest Oncol

Fiyinfolu Balogun
2026

Dual pancreatic carcinomas: clonally related or independent primaries?

Schoenfeld JD, Ravichandran V, Tarcan Z, Sahin-Ozkan H, Richards AL, Bilani N, Chou JF, O'Connor CA, et al.

NPJ Precis Oncol

sPARK LabWungki ParkEileen O'ReillyFiyinfolu Balogun
2026

Maximal Ablative Irradiation Because of Encasement for Patients With Locally Advanced Pancreatic Cancer: A Nonrandomized Clinical Trial

Reyngold M, Wei AC, O'Reilly EM, D'Angelica MI, Kingham TP, Soares KC, Varghese AM, White C, et al.

JAMA Surg

sPARK LabWungki ParkEileen O'ReillyFiyinfolu Balogun
2026

Neoantigen-reactive CD8+ T cell engagement marks exceptional survivors of pancreatic cancer

M Hilmi, JD Schoenfeld, W McKerrow, Y Elhanati, CA O'Connor, S Umeda, ...

bioRxiv, 2026.09. 17.752426

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2026

Pancreatic Cancer: Translating Tumor Biology into Actionability

Balogun FO, Sherman MH, Park W, Soares KC, Reyngold M, Schoenfeld JD, Singhal A, Iacobuzio-Donahue CA, et al.

Cancer Discov

sPARK LabWungki ParkEileen O'ReillyFiyinfolu BalogunJoshua Schoenfeld
2026

Pembrolizumab and olaparib in homologous-recombination-deficient metastatic pancreatic cancer: the phase 2 POLAR trial

W Park, CA O’Connor, JF Chou, M Hilmi, Z Tarcan, C Schwartz, M Larsen, ...

Nature Medicine, 1-11

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2026

Pembrolizumab and Olaparib in HRD Metastatic Pancreatic Cancer: The POLAR Trial

Park W (Corresponding Author), O’Reilly E, et al.

Nature Medicine

sPARK LabWungki ParkEileen O'ReillyFiyinfolu BalogunJoshua SchoenfeldMarc HilmiCatherine O'Connor
2026

POLQ-driven repair scars shape the immunogenic landscape of homologous recombination-deficient pancreatic cancer

Park W, Umeda S, Hilmi M, O'Connor C, Sharma R, Tezcan N, Zhang H, Zhu Y, et al.

bioRxiv

sPARK LabWungki ParkEileen O'ReillyFiyinfolu BalogunMarc HilmiCatherine O'Connor
2026

2223P First-line (1L) AZD0171+ durvalumab (D)+ chemotherapy (CT) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC): Phase II study results

S Chandana, A Ruiz-Casado, RA Gallego, AL Coveler, R El-Maraghi, ...

Annals of Oncology 36, S1235-S1236

Fiyinfolu Balogun
2025

Abstract A097: Impact of socioeconomic status on survival outcomes in patients with stage IV pancreatic adenocarcinoma: A race/ethnicity controlled analysis

A Erakky, S Nandakumar, M Waters, J Duque-Jimenez, A Awuah, M Lao, ...

Cancer Epidemiology, Biomarkers & Prevention 34 (9_Supplement), A097-A097

sPARK LabEileen O'ReillyFiyinfolu Balogun
2025

Abstract B044: Black and Hispanic patients with pancreatic ductal adenocarcinoma (PDAC) have worse overall survival than Asian and White patients with PDAC, despite having more …

JB Duque-Jimenez, AN Awuah, A Erakky, S Nandakumar, M Waters, ...

Cancer Research 85 (18_Supplement_3), B044-B044

sPARK LabEileen O'ReillyFiyinfolu Balogun
2025

Abstract B047: DNA Damage Repair (DDR) Variants Beyond BRCA/PALB2 in Pancreatic Adenocarcinoma (PDAC): Evaluation of Significance

CA O'Connor, JW Lee, E Harrold, AL Richards, D Muldoon, ...

Cancer Research 85 (18_Supplement_3), B047-B047

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2025

Adjuvant modified FOLFIRINOX for resected pancreatic adenocarcinoma: clinical insights and genomic features from a large contemporary cohort

Keane F, O'Connor C, Moss D, Chou JF, Perry MA, Crowley F, Saxena P, Chan A, et al.

J Natl Cancer Inst

sPARK LabWungki ParkEileen O'ReillyFiyinfolu BalogunJoshua SchoenfeldCatherine O'Connor
2025

Clinical utility and tissue concordance of circulating tumor DNA in pancreatic ductal adenocarcinoma

Keane F, Saadat LV, O'Connor CA, Chou JF, Bowman AS, Xu F, Crowley F, Debnath N, et al.

J Natl Cancer Inst

sPARK LabWungki ParkEileen O'ReillyFiyinfolu BalogunJoshua SchoenfeldCatherine O'Connor
2025

Clinico-genomic characterization of PALB2-mutated pancreatic adenocarcinoma.

JW Lee, CA O'Connor, E Harrold, AL Richards, F Velez-Cortes, D Moss, ...

Journal of Clinical Oncology 43 (16_suppl), 4169-4169

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2025

Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival

Varghese AM, Perry MA, Chou JF, Nandakumar S, Muldoon D, Erakky A, … Park W, …

Nature Medicine 31(2), 466–477

sPARK LabWungki ParkEileen O'ReillyFiyinfolu Balogun
2025

Fecal Immunochemical Tests (FIT) and Focus Groups: Tailoring Bilingual Cancer Screening Education

Haveric A, Balogun F, Gilliland J, Narang B, Gany F

J Community Health

Fiyinfolu Balogun
2025

Metastatic Epstein-Barr Virus-Associated Lymphoepithelioma-Like Carcinoma of Small Bowel Origin

JJ Tao, H Hibshoosh, SM Lagana, F Balogun, RA White

Case Reports in Oncology 18 (1), 1439-1446

Fiyinfolu Balogun
2025

Molecular differences in pancreatic ductal adenocarcinomas from black versus white patients

S Mandal, EA Teslow, M Huang, Y Yu, S Sridhar, HC Crawford, ...

Cancer Research Communications 5 (1), 128-137

Fiyinfolu Balogun
2025

Pembrolizumab and Olaparib (POLAR) Maintenance Therapy in Metastatic Pancreatic Cancer With or Without Homologous Repair Deficiency: A Biomarker Selected Phase II Trial

Park W, O'Connor C, Chou J, Hilmi M, Tarcan Z, Schwartz C, Larsen M, Chatila W, et al.

Res Sq

sPARK LabWungki ParkEileen O'ReillyFiyinfolu BalogunMarc Hilmi
2025

Toward Early Detection: A Scoping Review of Hepatocellular Cancer Surveillance in Sub-Saharan Africa

S Okeke, O Adewara, D Akoki, I Ijezie, M Abraham, D Irabor, F Balogun

Cancer Epidemiology, Biomarkers & Prevention 34 (12_Supplement), 29-29

Fiyinfolu Balogun
2025

1504MO Phase II trial of Pembrolizumab and OLApaRib (POLAR) maintenance for select patients (pts) with metastatic pancreatic cancer (mPC) with (A) homologous recombination …

W Park, C O’Connor, J Chou, C Schwartz, M Larsen, A Varghese, K Yu, ...

Annals of Oncology 35, S922

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2024

Abstract B042: Clinical and molecular characterization of Lynch syndrome-associated pancreas adenocarcinoma (PDAC)

E Harrold, CA O'Connor, D Lin, A Gazzo, H Walch, M Ranganathan, ...

Cancer Research 84 (2_Supplement), B042-B042

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2024

Abstract C104: Dual primary pancreas cancers–Related or independent lesions?

JD Schoenfeld, H Sahan-Ozkan, N Bilani, MI D'Angelica, WR Jarnagin, ...

Cancer Research 84 (2_Supplement), C104-C104

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2024

Adjuvant mFOLFIRINOX (mFFX) for resected pancreatic cancer (PC): Long term clinical and genomic outcomes.

F Keane, D Moss, CA O'Connor, M Perry, JF Chou, F Crowley, P Saxena, ...

Journal of Clinical Oncology 42 (16_suppl), 4170-4170

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2024

Lynch Syndrome and Somatic Mismatch Repair Variants in Pancreas Cancer

O'Connor CA, Harrold E, Lin D, Walch H, Gazzo A, Ranganathan M, Kane S, Keane F, et al.

JAMA Oncol

sPARK LabWungki ParkEileen O'ReillyFiyinfolu Balogun
2024

Precision medicine for pancreatic cancer: characterizing the clinicogenomic landscape and outcomes of KRAS G12C-mutated disease

Keane F, Chou JF, Walch H, Schoenfeld J, Singhal A, Cowzer D, Harrold E, O'Connor CA, et al.

J Natl Cancer Inst

sPARK LabWungki ParkEileen O'ReillyFiyinfolu Balogun
2024

Somatic mismatch repair deficiency in pancreas cancer (PC): Immune checkpoint blockade (ICB) outcomes and exploratory genomic analyses.

CA O'Connor, E Harrold, YT Lin, HS Walch, A Gazzo, SR Kane, F Keane, ...

Journal of Clinical Oncology 42 (16_suppl), 4144-4144

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2024

Tumor progression and tumor microenvironment of pancreas cancer ascites revealed by scRNA-seq and spatial transcriptomics

S Umeda, ER Karnoub, F Balogun, A Jiménez-Sánchez, ...

Cancer Research 84 (6_Supplement), 1273-1273

Fiyinfolu Balogun
2024

A single cell landscape of malignant pancreas cancer ascites

S Umeda, ER Karnoub, E Ziv, J Wu, C Cruz, W Park, F Balogun, ...

Cancer Research 83 (7_Supplement), 1241-1241

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2023

Adjuvant modified FOLFIRINOX (mFFX) for resected pancreatic cancer (PDAC): Real world outcomes (RWO).

F Keane, F Balogun, C O'Connor, F Crowley, A Chan, D Cowzer, JF Chou, ...

Journal of Clinical Oncology 41 (4_suppl), 685-685

sPARK LabEileen O'ReillyFiyinfolu BalogunWungki Park
2023

Africa Guidelines for Hepatocellular Carcinoma Buildup Process

Abou-Alfa GK, Afihene M, Capanu M, Li Y, Chou JF, Asombang A, Alatise OI, Bounedjar A, et al.

JCO Glob Oncol

Fiyinfolu Balogun
2023

Clinical utility of next generation sequencing (NGS) on circulating tumor DNA (ctDNA) in patients (pts) with pancreatic cancer (PC).

F Keane, L Saadat, C O'Connor, JF Chou, AR Brannon, D Cowzer, ...

Journal of Clinical Oncology 41 (16_suppl), 4154-4154

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2023

Evaluation of microsatellite instability status, a definitive predictive biomarker for immune checkpoint inhibitors (ICI), in underrepresented minorities (URM) with …

F Balogun, M Altoe, C O'Connor, N Chowdhury, A Cercek, C Lee, ...

Journal of Clinical Oncology 41 (16_suppl), 3538-3538

sPARK LabEileen O'ReillyFiyinfolu BalogunWungki Park
2023

Phase 2 trial of pembrolizumab and olaparib (POLAR) maintenance for patients (pts) with metastatic pancreatic cancer (mPDAC): Two cohorts B non-core homologous recombination …

W Park, C O'Connor, JF Chou, C Schwartz, AM Varghese, M Larsen, ...

Journal of Clinical Oncology 41 (16_suppl), 4140-4140

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2023

The Onc Docs: Partnering with Black cancer patients for cancer education.

F Balogun, O Balogun

Journal of Clinical Oncology 41 (16_suppl), e18681-e18681

Fiyinfolu Balogun
2023

1304P Characterizing the clinico-genomic landscape and outcomes of KRAS G12C mutated pancreas cancer

F Keane, W Park, A Varghese, F Balogun, K Yu, I El Dika, D Khalil, ...

Annals of Oncology 33, S1140

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2022

Abstract CT126: a phase 2 trial of first-line AZD0171+ durvalumab and chemotherapy (CT) in patients with metastatic pancreatic ductal adenocarcinoma (PDAC) and CD8+ T cell …

G O'Kane, T Macarulla, F Balogun, A Hollebecque, MJ Reilley, ...

Cancer Research 82 (12_Supplement), CT126-CT126

Fiyinfolu Balogun
2022

Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice

Park W, O'Connor CA, Bandlamudi C, Forman D, Chou JF, Umeda S, Reyngold M, Varghese AM, et al.

Clin Cancer Res

sPARK LabWungki ParkEileen O'ReillyFiyinfolu BalogunCatherine O'Connor
2022

When Radiotherapy and Immunotherapy Dance—Who Leads So as Not to Step on Toes?

F Balogun, D Raben

JAMA oncology 8 (2), 240-241

Fiyinfolu Balogun
2022

Development and assessment of a clinical calculator for estimating the likelihood of recurrence and survival among patients with locally advanced rectal cancer treated with …

MR Weiser, JF Chou, A Keshinro, WC Chapman Jr, PS Bauer, MG Mutch, ...

JAMA Network Open 4 (11), e2133457

Fiyinfolu Balogun
2021

Oral squamous cell carcinoma as a complication of treatment for recurrent high‐grade serous cancer

LE Moses, JM Rotsides, FO Balogun, MS Persky, FM Muggia, MJ Persky

The Laryngoscope 130 (11), 2607-2610

Fiyinfolu Balogun
2020

Abstract I14: Polymerase theta synthetic lethal interaction in homologous recombination-deficient pancreatic ductal adenocarcinoma

A Wang, A Zamperone, M Sohail, L Wang, F Balogun, J Li, E Zhao, ...

Cancer Research 79 (24_Supplement), I14-I14

Fiyinfolu Balogun
2019

Massive enoxaparin overdose partially reversed with low doses of protamine

J de Olano, F Balogun, C Waslsh, C Ramprasad, D Green, M Miller, ...

Clinical Toxicology 56 (10), 987-988

Fiyinfolu Balogun
2018

ISOLATED THROMBOCYTOSIS AND A MASS IN THE HEART

M Rufin, F Balogun, D Randlett

JOURNAL OF GENERAL INTERNAL MEDICINE 32, S522-S522

Fiyinfolu Balogun
2017

DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast

FO Balogun, AW Truman, SJ Kron

DNA repair 12 (9), 751-760

Fiyinfolu Balogun
2013

DNA Resection and Chromatin Remodeling in G1 Checkpoint Activation of Budding Yeast

FO Balogun

University of Chicago, Division of the Biological Sciences, and The Pritzker …

Fiyinfolu Balogun
2012

Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations

CL Liquori, MJ Berg, AM Siegel, E Huang, JS Zawistowski, TP Stoffer, ...

The American Journal of Human Genetics 73 (6), 1459-1464

Fiyinfolu Balogun
2003