Publications
Publications from the sPARK research community. Filter by member authorship or year.
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Clear filters430P CLDN18. 2 and KRAS signaling shape tumor states and immune microenvironment in pancreatic cancer (PC)
Annals of Oncology 37, S157
Abstract A042: ctDNA KRAS detection in pancreatic ductal adenocarcinoma: Platform concordance, sensitivity and clinical associations in a contemporary cohort
Cancer Research 86 (18_Supplement_2), A042-A042
Brain metastasis from KRAS wild-type pancreatic cancer and organoid correlates: a case report
J Gastrointest Oncol
Dual pancreatic carcinomas: clonally related or independent primaries?
NPJ Precis Oncol
Maximal Ablative Irradiation Because of Encasement for Patients With Locally Advanced Pancreatic Cancer: A Nonrandomized Clinical Trial
JAMA Surg
Neoantigen-reactive CD8+ T cell engagement marks exceptional survivors of pancreatic cancer
bioRxiv, 2026.09. 17.752426
Pancreatic Cancer: Translating Tumor Biology into Actionability
Cancer Discov
Pembrolizumab and olaparib in homologous-recombination-deficient metastatic pancreatic cancer: the phase 2 POLAR trial
Nature Medicine, 1-11
Pembrolizumab and Olaparib in HRD Metastatic Pancreatic Cancer: The POLAR Trial
Nature Medicine
POLQ-driven repair scars shape the immunogenic landscape of homologous recombination-deficient pancreatic cancer
bioRxiv
2223P First-line (1L) AZD0171+ durvalumab (D)+ chemotherapy (CT) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC): Phase II study results
Annals of Oncology 36, S1235-S1236
Abstract A097: Impact of socioeconomic status on survival outcomes in patients with stage IV pancreatic adenocarcinoma: A race/ethnicity controlled analysis
Cancer Epidemiology, Biomarkers & Prevention 34 (9_Supplement), A097-A097
Abstract B044: Black and Hispanic patients with pancreatic ductal adenocarcinoma (PDAC) have worse overall survival than Asian and White patients with PDAC, despite having more …
Cancer Research 85 (18_Supplement_3), B044-B044
Abstract B047: DNA Damage Repair (DDR) Variants Beyond BRCA/PALB2 in Pancreatic Adenocarcinoma (PDAC): Evaluation of Significance
Cancer Research 85 (18_Supplement_3), B047-B047
Adjuvant modified FOLFIRINOX for resected pancreatic adenocarcinoma: clinical insights and genomic features from a large contemporary cohort
J Natl Cancer Inst
Clinical utility and tissue concordance of circulating tumor DNA in pancreatic ductal adenocarcinoma
J Natl Cancer Inst
Clinico-genomic characterization of PALB2-mutated pancreatic adenocarcinoma.
Journal of Clinical Oncology 43 (16_suppl), 4169-4169
Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival
Nature Medicine 31(2), 466–477
Fecal Immunochemical Tests (FIT) and Focus Groups: Tailoring Bilingual Cancer Screening Education
J Community Health
Metastatic Epstein-Barr Virus-Associated Lymphoepithelioma-Like Carcinoma of Small Bowel Origin
Case Reports in Oncology 18 (1), 1439-1446
Molecular differences in pancreatic ductal adenocarcinomas from black versus white patients
Cancer Research Communications 5 (1), 128-137
Pembrolizumab and Olaparib (POLAR) Maintenance Therapy in Metastatic Pancreatic Cancer With or Without Homologous Repair Deficiency: A Biomarker Selected Phase II Trial
Res Sq
Toward Early Detection: A Scoping Review of Hepatocellular Cancer Surveillance in Sub-Saharan Africa
Cancer Epidemiology, Biomarkers & Prevention 34 (12_Supplement), 29-29
1504MO Phase II trial of Pembrolizumab and OLApaRib (POLAR) maintenance for select patients (pts) with metastatic pancreatic cancer (mPC) with (A) homologous recombination …
Annals of Oncology 35, S922
Abstract B042: Clinical and molecular characterization of Lynch syndrome-associated pancreas adenocarcinoma (PDAC)
Cancer Research 84 (2_Supplement), B042-B042
Abstract C104: Dual primary pancreas cancers–Related or independent lesions?
Cancer Research 84 (2_Supplement), C104-C104
Adjuvant mFOLFIRINOX (mFFX) for resected pancreatic cancer (PC): Long term clinical and genomic outcomes.
Journal of Clinical Oncology 42 (16_suppl), 4170-4170
Lynch Syndrome and Somatic Mismatch Repair Variants in Pancreas Cancer
JAMA Oncol
Precision medicine for pancreatic cancer: characterizing the clinicogenomic landscape and outcomes of KRAS G12C-mutated disease
J Natl Cancer Inst
Somatic mismatch repair deficiency in pancreas cancer (PC): Immune checkpoint blockade (ICB) outcomes and exploratory genomic analyses.
Journal of Clinical Oncology 42 (16_suppl), 4144-4144
Tumor progression and tumor microenvironment of pancreas cancer ascites revealed by scRNA-seq and spatial transcriptomics
Cancer Research 84 (6_Supplement), 1273-1273
A single cell landscape of malignant pancreas cancer ascites
Cancer Research 83 (7_Supplement), 1241-1241
Adjuvant modified FOLFIRINOX (mFFX) for resected pancreatic cancer (PDAC): Real world outcomes (RWO).
Journal of Clinical Oncology 41 (4_suppl), 685-685
Africa Guidelines for Hepatocellular Carcinoma Buildup Process
JCO Glob Oncol
Clinical utility of next generation sequencing (NGS) on circulating tumor DNA (ctDNA) in patients (pts) with pancreatic cancer (PC).
Journal of Clinical Oncology 41 (16_suppl), 4154-4154
Evaluation of microsatellite instability status, a definitive predictive biomarker for immune checkpoint inhibitors (ICI), in underrepresented minorities (URM) with …
Journal of Clinical Oncology 41 (16_suppl), 3538-3538
Phase 2 trial of pembrolizumab and olaparib (POLAR) maintenance for patients (pts) with metastatic pancreatic cancer (mPDAC): Two cohorts B non-core homologous recombination …
Journal of Clinical Oncology 41 (16_suppl), 4140-4140
The Onc Docs: Partnering with Black cancer patients for cancer education.
Journal of Clinical Oncology 41 (16_suppl), e18681-e18681
1304P Characterizing the clinico-genomic landscape and outcomes of KRAS G12C mutated pancreas cancer
Annals of Oncology 33, S1140
Abstract CT126: a phase 2 trial of first-line AZD0171+ durvalumab and chemotherapy (CT) in patients with metastatic pancreatic ductal adenocarcinoma (PDAC) and CD8+ T cell …
Cancer Research 82 (12_Supplement), CT126-CT126
Clinico-genomic Characterization of ATM and HRD in Pancreas Cancer: Application for Practice
Clin Cancer Res
When Radiotherapy and Immunotherapy Dance—Who Leads So as Not to Step on Toes?
JAMA oncology 8 (2), 240-241
Development and assessment of a clinical calculator for estimating the likelihood of recurrence and survival among patients with locally advanced rectal cancer treated with …
JAMA Network Open 4 (11), e2133457
Oral squamous cell carcinoma as a complication of treatment for recurrent high‐grade serous cancer
The Laryngoscope 130 (11), 2607-2610
Abstract I14: Polymerase theta synthetic lethal interaction in homologous recombination-deficient pancreatic ductal adenocarcinoma
Cancer Research 79 (24_Supplement), I14-I14
Massive enoxaparin overdose partially reversed with low doses of protamine
Clinical Toxicology 56 (10), 987-988
ISOLATED THROMBOCYTOSIS AND A MASS IN THE HEART
JOURNAL OF GENERAL INTERNAL MEDICINE 32, S522-S522
DNA resection proteins Sgs1 and Exo1 are required for G1 checkpoint activation in budding yeast
DNA repair 12 (9), 751-760
DNA Resection and Chromatin Remodeling in G1 Checkpoint Activation of Budding Yeast
University of Chicago, Division of the Biological Sciences, and The Pritzker …
Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations
The American Journal of Human Genetics 73 (6), 1459-1464