sPARK.
Vincenzo Nasca, MD
Research Scholar

Vincenzo Nasca, MD

PubMed →

Medical oncologist and research fellow at sPARK Lab working on multi-omic characterization of pancreatic and biliary tract cancers, to identify molecular vulnerabilities and mechanisms of therapeutic resistance to innovative treatments.

Recent publications

Clin Cancer Res · 2026ctDNA Detection with Low-Pass Whole-Genome Bisulfite Sequencing in RAS Wild-Type Metastatic Colorectal Cancer: An Exploratory Objective of the VALENTINO TrialOncologist · 2026Mucinous histology and resistance to immune checkpoint blockade in patients with microsatellite instability-high metastatic colorectal cancerOncologist · 2025First-line PD-1 +/- CTLA-4 blockade in patients with deficient mismatch repair and/or microsatellite instability-high metastatic colorectal cancerClin Cancer Res · 2024Negative Hyperselection of Patients with HER2+ and RAS Wild-Type Metastatic Colorectal Cancer Receiving Dual HER2 Blockade: the PRESSING-HER2 StudyJ Immunother Cancer · 2023Association of immune-related adverse events with the outcomes of immune checkpoint inhibitors in patients with dMMR/MSI-H metastatic colorectal cancerJ Immunother Cancer · 2023Outcomes and a prognostic classifier in patients with microsatellite instability-high metastatic gastric cancer receiving PD-1 blockade

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