Publications
Publications from the sPARK research community. Filter by member authorship or year.
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Clear filtersPancreatic cancer: a review (vol 326, pg 851, 2021)
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 326 (20), 2081-2081
Predicting immunotherapy outcomes under therapy in patients with advanced NSCLC using dNLR and its early dynamics
Eur J Cancer
Preliminary clinical and biologic results of GB1275, a first-in-class oral CD11b modulator, alone and with pembrolizumab, in advanced solid tumors (KEYNOTE A36).
Journal of Clinical Oncology 39 (15_suppl), 2505-2505
Real-world pan-cancer landscape of frameshift mutations (FSM) and their role in predicting responses to immune checkpoint inhibitors (ICI) in patients (pts) with tumors with …
Journal of Clinical Oncology 39 (15_suppl), 2599-2599
Targeting DNA damage repair pathways in pancreas cancer
Cancer Metastasis Rev
388 Preliminary results from KEYNOTE-A36, a study of GB1275, a first-in-class oral CD11b modulator, alone and with pembrolizumab or chemotherapy in specified advanced solid tumors
Journal for Immunotherapy of Cancer 8 (Suppl 3), A236-A236
75 Generalizability of potential biomarkers of response to CTLA-4 and PD-1 blockade therapy in cancer
Journal for ImmunoTherapy of Cancer 8 (Suppl 3)
A phase I/II study of GB1275, a first-in-class oral CD11b modulator, alone, and combined with pembrolizumab in specified advanced solid tumors or with chemotherapy in …
Journal of Clinical Oncology 38 (15_suppl), 3085-3085
Abstract CT247: A phase 1/2 study of GB1275, a first-in-class CD11b modulator, as monotherapy and with an anti-PD-1 antibody in specified advanced solid tumors or with …
Cancer Research 80 (16_Supplement), CT247-CT247
Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma
Cancer 126(17), 3939–3949
Association of the prognostic model iSEND with PD-1/L1 monotherapy outcome in non-small-cell lung cancer
Br J Cancer
Correction to: Outcomes associated with immune-related adverse events in metastatic non-small cell lung cancer treated with nivolumab: a pooled exploratory analysis from a global cohort
Cancer Immunol Immunother
Genetic algorithms to identify homologous recombination deficiency (HRD) in pancreas adenocarcinoma
Cancer Research 80 (16_Supplement), 3557-3557
Genomic methods identify homologous recombination deficiency in pancreas adenocarcinoma and optimize treatment selection
Clinical Cancer Research 26(13), 3239–3247
Landscape of DNA-damage-repair/homologous recombination deficiency (DDR/HRD) in hepatopancreaticobiliary (HPB) cancers.
Journal of Clinical Oncology 38 (15_suppl), 4620-4620
Outcomes associated with immune-related adverse events in metastatic non-small cell lung cancer treated with nivolumab: a pooled exploratory analysis from a global cohort
Cancer Immunology, Immunotherapy 69(7), 1177–1187
P854 Construction of the immune landscape of durable response to checkpoint blockade therapy by integrating publicly available datasets
Journal for ImmunoTherapy of Cancer 8 (Suppl 1), A5-A6
Pancreatic ductal adenocarcinoma (PDAC), BRCA: Detailed analysis and outcomes of cohort from Memorial Sloan Kettering Cancer Center (MSK).
Journal of Clinical Oncology 38 (4_suppl), 708-708
Phase II, open-label, randomized study of first-line zolbetuximab plus gemcitabine and nab-paclitaxel (GN) in Claudin 18.2–positive metastatic pancreatic cancer (mPC).
Journal of Clinical Oncology 38 (15_suppl), TPS4667-TPS4667
Reply to N. Fazio
J Clin Oncol
Young-onset pancreas cancer (PC) in patients less than or equal to 50 years old at Memorial Sloan Kettering (MSK): Descriptors, genomics, and outcomes.
Journal of Clinical Oncology 38 (4_suppl), 774-774
A phase 1/2 study of GB1275, a novel CD11b modulator, as monotherapy and with an anti-PD-1 antibody in specified advanced solid tumors or with chemotherapy in metastatic …
JOURNAL FOR IMMUNOTHERAPY OF CANCER 7
Axitinib plus pembrolizumab in patients with advanced sarcomas including alveolar soft-part sarcoma: a single-centre, single-arm, phase 2 trial
The Lancet Oncology 20(6), 837–848
Clinical and Immunological Implications of Frameshift Mutations in Lung Cancer
J Thorac Oncol
Clinical implications of circulating tumor DNA tumor mutational burden (ctDNA TMB) in non-small cell lung cancer
The Oncologist 24(6), 820–828
Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop
J Immunother Cancer
EP1. 01-61 iSEND Model as a Predictor of Efficacy in Immune Checkpoint Inhibitors for Non-Small Cell Lung Cancer: Fukushima Cohort
Journal of Thoracic Oncology 14 (10), S935
Extended mutational profiling by MSK-IMPACTTM identifies mutations predicting thromboembolic risk in patients with solid tumor malignancy
Blood 134, 633
Frameshift mutations (Fsindel) complement tumor mutation burden (TMB) in predicting survival after immune checkpoint inhibitors (ICI) in a pancancer analysis.
Journal of clinical oncology 37 (15_suppl), 2617-2617
Genomic profiling in pancreatic ductal adenocarcinoma and a pathway towards therapy individualization: A scoping review
Cancer Treat Rev
Homologous recombination deficiency (HRD): A biomarker for first-line (1L) platinum in advanced pancreatic ductal adenocarcinoma (PDAC).
Journal of Clinical Oncology 37 (15_suppl), 4132-4132
MA07. 02 early change of dNLR is correlated with outcomes in advanced NSCLC patients treated with immunotherapy
Journal of Thoracic Oncology 14 (10), S273
Perspectives: Neutrophil-to-lymphocyte Ratio as a Potential Biomarker in Immune Checkpoint Inhibitor for Non-Small-Cell Lung Cancer
Clin Lung Cancer
Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop
Journal for Immunotherapy of Cancer 7(1), 131
(P09) Combined Use of Radiosurgery With Concurrent PD-1/PD-L1 Inhibition For Metastatic Brain Lesions of NSCLC
International Journal of Radiation Oncology, Biology, Physics 101 (2), E24
A phase II trial of axitinib plus pembrolizumab for patients with advanced alveolar soft part sarcoma (ASPS) and other soft tissue sarcomas (STS).
Journal of clinical oncology 36 (15_suppl), 11547-11547
An inflammation paradox: Obesity vs. neutrophil-lymphocyte ratio in immunotherapy
Cancer Research 78 (13_Supplement), 701-701
Autoimmune haemolytic anaemia in a patient with advanced lung adenocarcinoma and chronic lymphocytic leukaemia receiving nivolumab and intravenous immunoglobulin
BMJ Case Rep
Complete response to ipilimumab and nivolumab therapy in a patient with extensive extrapulmonary high-grade small cell carcinoma of the pancreas and HIV infection
J Immunother Cancer
Cost-effectiveness of Osimertinib in the First-Line Treatment of Patients With EGFR-Mutated Advanced Non–Small Cell Lung Cancer
JAMA Oncology 4(8), 1080–1084
Derived neutrophil-to lymphocyte ratio (dNLR) change between baseline and cycle 2 is correlated with benefit during immune checkpoint inhibitors (ICI) in advanced non-small …
Annals of Oncology 29, viii508
Developing a Predictive Model for Clinical Outcomes of Advanced Non-Small Cell Lung Cancer Patients Treated With Nivolumab
Clin Lung Cancer
High pretreatment neutrophil-to-lymphocyte ratio (NLR) and its reactive increase as better predictors of poor clinical outcomes compared to tumor mutation burden (TMB) in solid …
Journal of Clinical Oncology 36 (15_suppl), e24109-e24109
MA19. 04 The Clinical Implication of Frameshift Indel Mutation Burden in Non-Small Cell Lung Cancer (NSCLC)
Journal of Thoracic Oncology 13 (10), S423
Neutrophil-lymphocyte-ratio to complement the prediction ability of PD-L1 expression for outcomes in patients with advanced non-small cell lung cancer treated with PD-1/PD-L1 …
Journal of Clinical Oncology 36 (15_suppl), e15102-e15102
P1. 01-68 Correlation of the lung immune prognostic index (LIPI) and PDL1 status with outcomes for immune checkpoint inhibitors in advanced NSCLC patients
Journal of Thoracic Oncology 13 (10), S488
P1. 04-19 Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict survival after immunotherapy in non-small cell lung cancer
Journal of Thoracic Oncology 13 (10), S532
P2. 01-82 Neutrophil-to-Lymphocyte Ratio Complements the Prognostic Ability of PD-L1 in Non-Small Cell Lung Cancer Treated with PD-1/PD-L1 Inhibitors
Journal of Thoracic Oncology 13 (10), S696
Predicting outcomes of advanced non-small cell lung cancer patients treated with PD-1/PDL-1 inhibitors: Independent international validation of the iSEND model.
Journal of Clinical Oncology 36 (15_suppl), 3015-3015
The Concept of Biosimilars: From Characterization to Evolution-A Narrative Review
Oncologist