Publications

Publications from the sPARK research community. Filter by member authorship or year.

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Immunogenomic characterization of biliary tract cancers: Biomarker enrichment for benefit to immune checkpoint blockade.

W Park, F Keane, C Bandlamudi, M Donoghue, P Tallón de Lara, ...

Journal of Clinical Oncology 40 (16_suppl), 4083-4083

sPARK LabEileen O'ReillyWungki Park
2022

Improving understanding of pancreatic cancer among patients using an animated patient’s guide to benefit informed decisions and health outcomes.

S Munigala, EM O'Reilly, DE Bakelman, J Holt, AH Ko, N Searle, A Gelrud

Journal of Clinical Oncology 40 (16_suppl), e16282-e16282

Eileen O'Reilly
2022

Incidence of Pancreatic Cancer by Age and Sex in the US From 2000 to 2018

F Keane, M Du, EM O’Reilly

Jama 327 (14), 1401-1402

Eileen O'Reilly
2022

Induction FOLFIRINOX for patients with locally unresectable pancreatic ductal adenocarcinoma

McIntyre CA, Cohen NA, Goldman DA, Gonen M, Sadot E, O'Reilly EM, Varghese AM, Yu KH, et al.

J Surg Oncol

Eileen O'Reilly
2022

Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of "Second Hit" in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma

Zheng-Lin B, Rainone M, Varghese AM, Yu KH, Park W, Berger M, Mehine M, Chou J, et al.

Mol Diagn Ther

sPARK LabWungki ParkEileen O'Reilly
2022

Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of “Second Hit” in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma: B …

B Zheng-Lin, M Rainone, AM Varghese, KH Yu, W Park, M Berger, ...

Molecular Diagnosis & Therapy 26 (6), 645-653

sPARK LabEileen O'ReillyWungki Park
2022

Mo1225: ACUTE PANCREATITIS CAN UNMASK UNDERLYING PANCREATIC ADENOCARCINOMA IN PATIENTS WITH UNCLEAR ETIOLOGY OF PANCREATITIS: A MULTICENTER ELECTRONIC HEALTH RESEARCH NETWORK …

RR Singh, A Klein, EM O'Reilly

Gastroenterology 162 (7), S-733

Eileen O'Reilly
2022

Molecular characterization of gallbladder cancer

NA Giraldo, A Mohanty, C Vanderbilt, R Brannon, R Benayed, E Vakiani, ...

Cancer Research 82 (12_Supplement), 82-82

Eileen O'Reilly
2022

Multi-institutional comparison of ablative radiation therapy in 5 versus 15-25 fractions for locally advanced pancreatic cancer

M Reyngold, E O'Reilly, R Herrera, A Kaiser, M Zinovoy, PB Romesser, ...

International Journal of Radiation Oncology, Biology, Physics 114 (3), S106

Eileen O'Reilly
2022

Neo‐adjuvant FOLFIRINOX in borderline resectable and locally advanced pancreatic adenocarcinoma

S Temraz, F Nassar, MS Hammoud, D Mukherji, EM O'Reilly, H Dbouk, ...

Asia‐Pacific Journal of Clinical Oncology 18 (6), 735-742

Eileen O'Reilly
2022

Neoadjuvant radiotherapy after (m) FOLFIRINOX for borderline resectable pancreatic adenocarcinoma: a TAPS consortium study

QP Janssen, JL van Dam, LR Prakash, D Doppenberg, CH Crane, ...

Journal of the National Comprehensive Cancer Network 20 (7), 783-791. e1

Eileen O'Reilly
2022

Overall Survival Results From the POLO Trial: A Phase III Study of Active Maintenance Olaparib Versus Placebo for Germline BRCA-Mutated Metastatic Pancreatic Cancer

Kindler HL, Hammel P, Reni M, Van Cutsem E, Macarulla T, Hall MJ, Park JO, Hochhauser D, et al.

J Clin Oncol

Eileen O'Reilly
2022

P-22 phase III study (daNIS-2) of the anti–TGF-β monoclonal antibody NIS793 with nab-paclitaxel/gemcitabine vs nab-paclitaxel/gemcitabine alone in patients with first-line …

E O'Reilly, T Golan, M Ikeda, M Milella, J Taieb, Z Wainberg, L Wang, ...

Annals of Oncology 33, S254

Eileen O'Reilly
2022

Pancreatic cancer: Cutaneous metastases, clinical descriptors and outcomes.

EM O'Reilly

Journal of Clinical Oncology 40 (4), 615-615

Eileen O'Reilly
2022

Persistent Disparities in Treatment and Survival for Patients with Pancreatic Cancer Despite Insurance Expansion Policies

L Saadat, J Chou, M Gonen, K Soares, V Balachandran, TP Kingham, ...

HPB 24, S386

Eileen O'Reilly
2022

Phase 2 open-label study of pembrolizumab plus lenvatinib and belzutifan in patients with advanced solid tumors.

RK Kelley, E Van Cutsem, MS Lee, I Wolf, M Fakih, J de Vos-Geelen, ...

Journal of Clinical Oncology 40 (4_suppl), TPS669-TPS669

Eileen O'Reilly
2022

Phase I trial of adjuvant autogene cevumeran, an individualized mRNA neoantigen vaccine, for pancreatic ductal adenocarcinoma.

VP Balachandran, LA Rojas, Z Sethna, K Soares, E Derhovanessian, ...

Journal of Clinical Oncology 40 (16_suppl), 2516-2516

Eileen O'Reilly
2022

Phase III study (daNIS-2) of the anti–TGF-β monoclonal antibody (mAb) NIS793 with nab-paclitaxel/gemcitabine (NG) versus NG alone in patients (pts) with first-line metastatic …

EM O'Reilly, T Golan, M Ikeda, M Milella, J Taieb, ZA Wainberg, LW Wang, ...

Journal of Clinical Oncology 40 (16_suppl), TPS4193-TPS4193

Eileen O'Reilly
2022

Plasma Protein Biomarkers in Advanced or Metastatic Colorectal Cancer Patients Receiving Chemotherapy With Bevacizumab or Cetuximab: Results from CALGB 80405 (Alliance)

Nixon AB, Sibley AB, Liu Y, Hatch AJ, Jiang C, Mulkey F, Starr MD, Brady JC, et al.

Clin Cancer Res

Eileen O'Reilly
2022

Precision approaches to pancreatic cancer therapy: what now and what next?

F Keane, W Park, EM O’Reilly

Current Treatment Options in Gastroenterology 20 (3), 406-428

sPARK LabEileen O'ReillyWungki Park
2022

Precision Medicine and Immunotherapy in GI Cancers

O'Reilly EM, Ko AH

J Clin Oncol

Eileen O'Reilly
2022

Radiation Therapy (RT) Quality Assurance (QA) Analysis of Alliance A021501: Preoperative mFOLFIRINOX or mFOLFIRINOX plus Hypofractionated Radiation Therapy for Borderline …

L Tchelebi, KS Smith, Q Shi, T Fitzgerald, MD Chuong, T Zemla, E O'Reilly, ...

International Journal of Radiation Oncology, Biology, Physics 114 (3), S105-S106

Eileen O'Reilly
2022

Real-world clinical outcomes of patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) treated with liposomal irinotecan-based regimens: Impact of prior irinotecan …

KH Yu, P Cockrum, A Surinach, N Lamarre, S Wang, EM O'Reilly

Journal of Clinical Oncology 40 (4_suppl), 580-580

Eileen O'Reilly
2022

Salvage ablative radiation therapy for loco-regionally recurrent pancreatic ductal adenocarcinoma following surgical resection.

V Ng, M Zinovoy, C Hajj, PB Romesser, AJC Wu, JJ Cuaron, WR Jarnagin, ...

Journal of Clinical Oncology 40 (4_suppl), 552-552

Eileen O'Reilly
2022

Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial

Padrón LJ, Maurer DM, O'Hara MH, O'Reilly EM, Wolff RA, Wainberg ZA, Ko AH, Fisher G, et al.

Nat Med

Eileen O'Reilly
2022

Stereotactic ablative radiation for pancreatic cancer on a 1.5 áTelsa magnetic resonance-linac system

KR Tringale, N Tyagi, PB Romesser, A Wu, EM O'Reilly, AM Varghese, ...

Physics and Imaging in Radiation Oncology 24, 88-94

sPARK LabEileen O'ReillyWungki Park
2022

Supporting Patients with Cancer after Dobbs v. Jackson Women’s Health Organization

AG Shuman, MS Aapro, B Anderson, K Arbour, PC Barata, A Bardia, ...

The Oncologist 27 (9), 711-713

Eileen O'Reilly
2022

Survival in Young-Onset Metastatic Colorectal Cancer: Findings From Cancer and Leukemia Group B (Alliance)/SWOG 80405

Lipsyc-Sharf M, Zhang S, Ou FS, Ma C, McCleary NJ, Niedzwiecki D, Chang IW, Lenz HJ, et al.

J Natl Cancer Inst

Eileen O'Reilly
2022

The frequency of second primary malignancies and colonic polyps in Lynch syndrome with MSI tumors following immune checkpoint blockade.

E Harrold, Z Patel, A Maio, A Cercek, R Yaeger, NH Segal, DL Reidy, ...

Journal of Clinical Oncology 40 (16_suppl), 10505-10505

Eileen O'Reilly
2022

The lung pro-thrombotic niche drives cancer-associated thromboembolism and metastasis via extracellular vesicle ITGB2.

S Lucotti, Y Ogitani, CM Kenific, L Bojmar, M Cioffi, P Lauritzen, H Molina, ...

CANCER RESEARCH 82 (22), 129-129

Eileen O'Reilly
2022

The lung pro-thrombotic niche drives cancer-associated thromboembolism via exosomal ITGB2

S Lucotti, Y Ogitani, CM Kenific, L Bojmar, M Cioffi, P Lauritzen, H Molina, ...

Cancer Research 82 (12_Supplement), 3138-3138

Eileen O'Reilly
2022

Timing of onset of systemic treatment in asymptomatic patients with metastatic pancreatic cancer: An international expert survey and case-vignette study.

S Augustinus, HWM Van Laarhoven, GA Cirkel, JW de Groot, ...

Journal of Clinical Oncology 40 (16_suppl), e16256-e16256

Eileen O'Reilly
2022

Tremelimumab and durvalumab in the treatment of unresectable, advanced hepatocellular carcinoma

TB de Castria, DN Khalil, JJ Harding, EM O’Reilly, GK Abou-Alfa

Future Oncology 18 (33), 3769-3782

Eileen O'Reilly
2022

Venous Thromboprophylaxis in Surgical Oncology Patients: The Importance of Risk Assessment in the Context of Limited Evidence

Snyder RA, O'Reilly EM

J Clin Oncol

Eileen O'Reilly
2022

Zenocutuzumab, a HER2xHER3 Bispecific Antibody, Is Effective Therapy for Tumors Driven by NRG1 Gene Rearrangements

Schram AM, Odintsov I, Espinosa-Cotton M, Khodos I, Sisso WJ, Mattar MS, Lui AJW, Vojnic M, et al.

Cancer Discov

Eileen O'Reilly
2022

Zolbetuximab plus gemcitabine and nab-paclitaxel (GN) in first-line treatment of claudin 18.2-positive metastatic pancreatic cancer (mPC): Phase 2, open-label, randomized study.

W Park, EM O'Reilly, J Furuse, CP Li, DY Oh, R Garcia-Carbonero, G Roth, ...

Journal of Clinical Oncology 40 (16_suppl), TPS4186-TPS4186

sPARK LabEileen O'ReillyWungki Park
2022

1467P POLO: Long-term safety and tolerability of olaparib for patients with a germline BRCA mutation and metastatic pancreatic cancer

D Arnold, T Golan, P Hammel, M Reni, E Van Cutsem, TM Mercade, ...

Annals of Oncology 32, S1085-S1086

Eileen O'Reilly
2021

1468P POLO: Subsequent therapy after maintenance olaparib in patients with a germline BRCA mutation and metastatic pancreatic cancer

T Golan, P Hammel, M Reni, E Van Cutsem, TM Mercade, MJ Hall, ...

Annals of Oncology 32, S1086-S1087

Eileen O'Reilly
2021

343 Multiomic biomarker signatures identify subsets of patients who may benefit from either nivolumab or sotigalimab in combination with chemotherapy in metastatic pancreatic …

D Maurer, JX Yu, K Sklodowski, M Tognetti, L Reiter, R Bruderer, ...

Journal for ImmunoTherapy of Cancer 9 (Suppl 2)

Eileen O'Reilly
2021

A Review of Pancreatic Cancer-Reply

Park W, Chawla A, O'Reilly EM

JAMA

sPARK LabWungki ParkEileen O'Reilly
2021

Abstract No. 86 Treatment of pancreatic cancer by intra-arterial injection of an emulsion of lipiodol and bumetanide (an anti-glycolytic drug) in a transgenic mutated pig model …

H Yarmohammadi, A Elsakka, F Nurili, A Maxwell, F Ridouani, E Ziv, ...

Journal of Vascular and Interventional Radiology 32 (5), S38

Eileen O'Reilly
2021

Alliance A021501: preoperative mFOLFIRINOX or mFOLFIRINOX plus hypofractionated radiation therapy (RT) for borderline resectable (BR) adenocarcinoma of the pancreas.

MHG Katz, Q Shi, JP Meyers, JM Herman, M Choung, BM Wolpin, ...

Journal of Clinical Oncology 39 (3_suppl), 377-377

Eileen O'Reilly
2021

Alliance/CALGB 80802: Impact of hepatitis C (HCV) on doxorubicin (DO)+ sorafenib (S) versus S in patients (pts) with advanced hepatocellular carcinoma (aHCC).

IH El Dika, SM Geyer, AB Nixon, F Innocenti, Q Shi, SB Jacobson, ...

Journal of Clinical Oncology 39 (3_suppl), 325-325

Eileen O'Reilly
2021

Assessment of ADI-PEG 20 and modified FOLFOX6 in advanced hepatocellular carcinoma patients: Results of an international, single-arm, phase 2 study

JJ Harding, TS Yang, YY Chen, YH Feng, CJ Yen, CL Ho, WT Huang, ...

Cancer 127 (24), 4585

Eileen O'Reilly
2021

Assessment of pegylated arginine deiminase and modified FOLFOX6 in patients with advanced hepatocellular carcinoma: Results of an international, single-arm, phase 2 study

Harding JJ, Yang TS, Chen YY, Feng YH, Yen CJ, Ho CL, Huang WT, El Dika I, et al.

Cancer

Eileen O'Reilly
2021

Association of ablative radiation therapy with survival among patients with inoperable pancreatic cancer

Reyngold M, O'Reilly EM, Varghese AM, Fiasconaro M, Zinovoy M, … Park W, …

JAMA Oncology 7(5), 735–738

sPARK LabWungki ParkEileen O'Reilly
2021

Baseline level and early on-treatment clearance of circulating mutant KRAS in metastatic pancreatic ductal adenocarcinoma treated with chemotherapy with or …

JE Till, A Abdalla, N Bhagwat, TA Black, Z Wang, SS Yee, PF Gherardini, ...

Journal of Clinical Oncology 39 (15_suppl), 4122-4122

Eileen O'Reilly
2021

CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label …

MH O'Hara, EM O'Reilly, G Varadhachary, RA Wolff, ZA Wainberg, AH Ko, ...

The lancet oncology 22 (1), 118-131

Eileen O'Reilly
2021

Clarity Plus Confidence: Leveraging eConsent to Assess Participant Agency in the Consent Process

MR O'Shea, M Buckley, J Wang, J Galle, M Lin, M Koch, J Lengfellner, ...

JOURNAL OF EMPIRICAL RESEARCH ON HUMAN RESEARCH ETHICS 16 (3), NP3-NP3

Eileen O'Reilly
2021

Clinical trials of systemic chemotherapy for resectable pancreatic cancer: a review

MN Mavros, D Moris, PJ Karanicolas, MHG Katz, EM O’Reilly, TM Pawlik

JAMA surgery 156 (7), 663-672

Eileen O'Reilly
2021