Publications

Publications from the sPARK research community. Filter by member authorship or year.

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Has management of locally advanced intrahepatic cholangiocarcinoma evolved with the evidence? Trends and practice patterns from the National Cancer Database

LE Schlehner, RJ Ellis, HL Kalvin, TP Kingham, KC Soares, MI D'Angelica, ...

ANNALS OF SURGICAL ONCOLOGY 31 (1), S197-S198

Eileen O'Reilly
2024

Has management of locally advanced intrahepatic cholangiocarcinoma evolved with the evidence? Trends and practice patterns from the National Cancer Database.

LE Schleimer, HL Kalvin, TP Kingham, K Soares, MI D'Angelica, ...

Journal of Clinical Oncology 42 (3_suppl), 464-464

Eileen O'Reilly
2024

Immune checkpoint blockade induced sarcoid-like reaction mimicking progression of disease in a patient with microsatellite instable colorectal cancer: case report and review of …

F Keane, E Yogiaveetil, B Kezlarian, M Lagratta, NH Segal, G Abou-Alfa, ...

Journal of Gastrointestinal Oncology 15 (1), 500

Eileen O'Reilly
2024

Improved Clinical Staging System for Localized Pancreatic Cancer Using the ABC Factors: A TAPS Consortium Study

Dekker EN, van Dam JL, Janssen QP, Besselink MG, DeSilva A, Doppenberg D, van Eijck CHJ, Nasar N, et al.

J Clin Oncol

Eileen O'Reilly
2024

Improved Survival With Adjuvant Cyclooxygenase 2 Inhibition in PIK3CA-Activated Stage III Colon Cancer: CALGB/SWOG 80702 (Alliance)

Nowak JA, Twombly T, Ma C, Shi Q, Haruki K, Fujiyoshi K, Väyrynen J, Zhao M, et al.

J Clin Oncol

Eileen O'Reilly
2024

Inflammation, physical activity, and disease-free survival in stage III colon cancer: Cancer and Leukemia Group B–Southwest Oncology Group 80702 (Alliance)

JC Brown, C Ma, Q Shi, F Couture, P Kuebler, P Kumar, B Tan, ...

JNCI: Journal of the National Cancer Institute 116 (12), 2032-2039

Eileen O'Reilly
2024

Inter-reader agreement of imaging response after neoadjuvant chemotherapy in pancreatic ductal adenocarcinoma

JS Heiselman, N Horvat, B Agridag-Upcinar, O Yildirim, BL Ecker, ...

Annals of Surgical Oncology 31 (1), S173-S174

Eileen O'Reilly
2024

Inter-reader variability of imaging biomarkers for therapeutic response in pancreatic ductal adenocarcinoma.

JS Heiselman, N Horvat, B Agridag-Upcinar, O Yildirim, BL Ecker, ...

Journal of Clinical Oncology 42 (3_suppl), 700-700

Eileen O'Reilly
2024

Intrahepatic cholangiocarcinoma: Recurrence patterns, genomics and survival.

P Chandra, Y Song, EN Drill, ACC Wei, NE Kemeny, A Cercek, ...

Journal of Clinical Oncology 42 (3_suppl), 570-570

sPARK LabEileen O'ReillyWungki Park
2024

Intrahepatic Cholangiocarcinoma: Recuurence Patterns, Genomics and Survival

P Chandra, Y Song, E Drill, AC Wei, N Kemeny, A Cercek, L Connell, ...

Annals of Surgical Oncology 31 (1), S166-S167

sPARK LabEileen O'ReillyWungki Park
2024

Kinetics of CA19-9 decline in a randomized phase III study of irinotecan liposome injection, oxaliplatin, 5-fluorouracial/leucovorin (NALIRIFOX) or nab-paclitaxel plus …

SR Chandana, ZA Wainberg, D Melisi, T Macarulla, RA Pazo Cid, ...

Journal of Clinical Oncology 42 (3_suppl), 687-687

Eileen O'Reilly
2024

KRAS Variants Are Associated With Survival Outcomes and Genomic Alterations in Biliary Tract Cancers

Gelfer R, Gulla A, Kalvin HL, Song Y, Harding J, Abou-Alfa GK, O'Reilly EM, Park W, et al.

JCO Precis Oncol

sPARK LabWungki ParkEileen O'Reilly
2024

LBA26 SOLARIS (Alliance A021703): A multicenter double-blind phase III randomized clinical trial (RCT) of vitamin D (VitD) combined with standard chemotherapy plus bevacizumab …

K Ng, FS Ou, T Zemla, N McCleary, A Kalyan, M Shusterman, ...

Annals of Oncology 35, S1219

Eileen O'Reilly
2024

Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial

Pant S, Wainberg ZA, Weekes CD, Furqan M, Kasi PM, Devoe CE, Leal AD, Chung V, et al.

Nat Med

Eileen O'Reilly
2024

Lynch Syndrome and Somatic Mismatch Repair Variants in Pancreas Cancer

O'Connor CA, Harrold E, Lin D, Walch H, Gazzo A, Ranganathan M, Kane S, Keane F, et al.

JAMA Oncol

sPARK LabWungki ParkEileen O'ReillyFiyinfolu Balogun
2024

Morbidity and mortality in patients with stage IV pancreatic adenocarcinoma and acute cholangitis: Outcomes and risk prognostication

Singh I, Chou JF, Capanu M, Park J, Yu KH, Varghese AM, Park W, Zervoudakis A, et al.

Pancreatology

sPARK LabWungki ParkEileen O'Reilly
2024

Multi-institutional comparison of ablative 5-fraction mr-guided online adapted vs. 15/25-fraction ct-guided offline adapted radiation therapy for locally advanced pancreas cancer

MD Chuong, E O’Reilly, R Herrera, M Zinovoy, KE Mittauer, M Rubens, ...

International Journal of Radiation Oncology, Biology, Physics 120 (2), S142

Eileen O'Reilly
2024

Multi-parametric atlas of the pre-metastatic liver for prediction of metastatic outcome in early-stage pancreatic cancer

Bojmar L, Zambirinis CP, Hernandez JM, Chakraborty J, Shaashua L, Kim J, Johnson KE, Hanna S, et al.

Nat Med

Eileen O'Reilly
2024

NALIRIFOX in the frontline for metastatic pancreatic cancer: evidence beyond NAPOLI 3

Wainberg ZA, M O'Reilly E

Nat Rev Clin Oncol

Eileen O'Reilly
2024

NALIRIFOX Versus FOLFOX as First-oLine Treatment of Metastatic Pancreatic Ductal Adenocarcinoma (mPDAC): Real-World Comparative Overall (OS) Survival Analysis

E O'Reilly, J Li, M DerSarkissian, R Chang, M Cheng, L Yu, D Rane, ...

PHARMACOEPIDEMIOLOGY AND DRUG SAFETY 33, 176-176

Eileen O'Reilly
2024

NALIRIFOX versus nab-paclitaxel and gemcitabine (Gem plus NabP) in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma (mPDAC): Subgroup analysis of …

T Macarulla Mercade, RA Pazo Cid, M Womack, A Cubillo Gracian, ...

ANNALS OF ONCOLOGY 35, S135-S136

Eileen O'Reilly
2024

NALIRIFOX versus nab-paclitaxel and gemcitabine in treatment-naïve patients with metastatic pancreatic ductal adenocarcinoma (mPDAC): Updated overall survival analysis with 29 …

MA Hussein, G Khan, SR Chandana, RA Pazo Cid, I Kiss, J Gallego, ...

Journal of Clinical Oncology 42 (16_suppl), 4136-4136

Eileen O'Reilly
2024

Next-generation therapies for pancreatic cancer

CW Buckley, EM O’Reilly

Expert review of gastroenterology & hepatology 18 (1-3), 55-72

Eileen O'Reilly
2024

Nivolumab monotherapy or combination with ipilimumab with or without cobimetinib in previously treated patients with pancreatic adenocarcinoma (CheckMate 032)

M Callahan, A Amin, FJ Kaye, MA Morse, MH Taylor, KJ Peltola, ...

Journal for immunotherapy of cancer 12 (2), e007883

Eileen O'Reilly
2024

Phase I/II first-in-human study to evaluate the safety and efficacy of tissue factor-ADC MRG004A in patients with solid tumors.

W Park, J Zhang, F Dayyani, J Shan, R Liu, R Guo, EM O'Reilly, Z Liu, ...

Journal of Clinical Oncology 42 (16_suppl), 3002-3002

sPARK LabEileen O'ReillyWungki Park
2024

Phase Ib/II, global, open-label, randomized evaluation of atezolizumab (atezo) plus etrumadenant (etruma) plus chemotherapy (chemo) vs chemo alone in MORPHEUS-PDAC

KP Kim, MP Sarvise, T Macarulla, A Alistar, E O'Reilly, M Boakye, ...

CANCER RESEARCH 84 (7)

Eileen O'Reilly
2024

Phase Ib/II, global, open-label, randomized evaluation of atezolizumab (atezo)+ etrumadenant (etruma)+ chemotherapy (chemo) vs chemo alone in MORPHEUS-PDAC

K Kim, M Ponz-Sarvise, T Macarulla, A Alistar, EM O’Reilly, M Boakye, ...

Liver 1 (4), 2.0

Eileen O'Reilly
2024

Plant-based diet and survival among patients with metastatic colorectal cancer: Findings from CALGB/SWOG 80405 (Alliance)

E Cheng, FS Ou, C Ma, AP Venook, HJ Lenz, EM O’Reilly, PT Campbell, ...

Cancer Research 84 (6_Supplement), 2200-2200

Eileen O'Reilly
2024

Postoperative adverse events following neoadjuvant therapy and surgery for borderline resectable pancreatic cancer in a phase 2 clinical trial (alliance A021501)

RA Snyder, TJ Zemla, Q Shi, D Segovia, SA Ahmad, EM O’Reilly, ...

Annals of surgical oncology 31 (10), 7033-7042

Eileen O'Reilly
2024

Postoperative complications following neoadjuvant therapy and surgery in a phase 2 borderline resectable pancreatic cancer clinical trial (Alliance A021501).

RA Snyder, TJ Zemla, Q Shi, DI Segovia, S Ahmad, EM O'Reilly, ...

Journal of Clinical Oncology 42 (3_suppl), 664-664

Eileen O'Reilly
2024

Precision medicine for pancreatic cancer: characterizing the clinicogenomic landscape and outcomes of KRAS G12C-mutated disease

Keane F, Chou JF, Walch H, Schoenfeld J, Singhal A, Cowzer D, Harrold E, O'Connor CA, et al.

J Natl Cancer Inst

sPARK LabWungki ParkEileen O'ReillyFiyinfolu Balogun
2024

Quality of life (QOL) for patients with esophageal cancer receiving trimodality therapy with induction chemotherapy, chemoradiation, and surgery: Results from CALGB 80803 …

KA Goodman, AC Dueck, B Fruth, AM Noonan, A Shergill, TS Bekaii-Saab, ...

Journal of Clinical Oncology 42 (3_suppl), 283-283

Eileen O'Reilly
2024

Radiation Quality Control in the PROSPECT Trial

HJ Mamon, Q Shi, KS Smith, B Colgrove, J Quigley, G Nelson, M Weiser, ...

International Journal of Radiation Oncology, Biology, Physics 120 (2), S117

Eileen O'Reilly
2024

Radiation therapy quality assurance analysis of alliance A021501: preoperative mFOLFIRINOX or mFOLFIRINOX plus hypofractionated radiation therapy for borderline resectable …

LT Tchelebi, D Segovia, K Smith, Q Shi, TJ Fitzgerald, MD Chuong, ...

International Journal of Radiation Oncology* Biology* Physics 120 (1), 111-119

Eileen O'Reilly
2024

Salvage Ablative Radiotherapy for Isolated Local Recurrence of Pancreatic Adenocarcinoma following Definitive Surgery

Dee EC, Ng VC, O'Reilly EM, Wei AC, Lobaugh SM, Varghese AM, Zinovoy M, Romesser PB, et al.

J Clin Med

sPARK LabWungki ParkEileen O'Reilly
2024

Salvage hepatic artery infusion chemotherapy after first-line systemic failure in patients with unresectable cholangiocarcinoma.

N Nasar, M Armstrong, JF Chou, M Gonen, K Soares, VP Balachandran, ...

Journal of Clinical Oncology 42 (3_suppl), 522-522

sPARK LabEileen O'ReillyWungki Park
2024

Second-line chemotherapy in localized pancreatic cancer: a systematic review and meta-analysis

EN Dekker, RR Narayan, MG Besselink, CH van Eijck, MY Homs, ...

HPB 26, S298-S299

Eileen O'Reilly
2024

Somatic mismatch repair deficiency in pancreas cancer (PC): Immune checkpoint blockade (ICB) outcomes and exploratory genomic analyses.

CA O'Connor, E Harrold, YT Lin, HS Walch, A Gazzo, SR Kane, F Keane, ...

Journal of Clinical Oncology 42 (16_suppl), 4144-4144

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2024

Starting at the Front Line in Metastatic Pancreatic Cancers: As New Options Emerge, How Do You Select and Sequence?

ZA Wainberg, T Bekaii-Saab, E O'Reilly, S Pant

Oncology 38 (9), 352-355

Eileen O'Reilly
2024

Survival after surgery for LAPC depends on post-induction CA19-9, CA19-9 decrease, performance status

E Dekker, D van Klaveren, Q Janssen, M Besselink, M Katz, E O’Reilly, ...

HPB 26, S699-S700

Eileen O'Reilly
2024

SWI/SNF Complex-Deficient Undifferentiated Carcinoma of the Pancreas: Clinicopathologic and Genomic Analysis

Yavas A, Ozcan K, Adsay NV, Balci S, Tarcan ZC, Hechtman JF, Luchini C, Scarpa A, et al.

Mod Pathol

sPARK LabWungki ParkEileen O'Reilly
2024

T cell responses and clinical outcomes in pancreatic and colorectal cancer patients with minimal residual disease in AMPLIFY-201, a phase 1 trial of a first-in-class amphiphile …

ZA Wainberg, S Pant, CD Weekes, M Furqan, PM Kasi, CE Devoe, ...

CANCER RESEARCH 84 (2)

Eileen O'Reilly
2024

Targeting KRAS in cancer

Singhal A, Li BT, O'Reilly EM

Nat Med

Eileen O'Reilly
2024

Therapeutic developments in pancreatic cancer

Hu ZI, O'Reilly EM

Nat Rev Gastroenterol Hepatol

Eileen O'Reilly
2024

115 Comprehensive spatial, transcriptomic, and genomic analysis of immunogenic biliary tract cancer

W Park, F Keane, HS Ozkan, A Richards, V Rudneva, D Khalil, K Soares, ...

Journal for ImmunoTherapy of Cancer 11 (Suppl 1)

sPARK LabEileen O'ReillyWungki Park
2023

1618P Durable efficacy of zenocutuzumab, a HER2 x HER3 bispecific antibody, in advanced NRG1 fusion positive (NRG1+) pancreatic ductal adenocarcinoma (PDAC)

A Schram, T Macarulla, J Cleary, C Neuzillet, D Arnold, KA Reiss, ...

Annals of Oncology 34, S895-S896

Eileen O'Reilly
2023

1619P Health-related quality of life with nalirifox versus nab-paclitaxel+ gemcitabine in treatment-naive patients with metastatic pancreatic ductal adenocarcinoma (mPDAC …

D Melisi, T Macarulla, C de la Fouchardiere, RAP Cid, S Chandana, ...

Annals of Oncology 34, S896-S897

Eileen O'Reilly
2023

1626P A novel endoscopic ultrasound guided extended-release siRNA implant targeting KRASG12D/V in localized pancreatic cancer

AM Varghese, T Golan, M Schattner, C Ang, M Gutierrez, M Passhak, ...

Annals of Oncology 34, S901

Eileen O'Reilly
2023

597P Surgical quality for patients (pts) treated with neoadjuvant chemotherapy vs chemoradiation for locally advanced rectal cancer (LARC): PROSPECT (NCCTG N1048, alliance)

M Weiser, Q Shi, GJ Chang, L Hakki, J Goldberg, R Auer, M Gollub, ...

Annals of Oncology 34, S431-S432

Eileen O'Reilly
2023

765 NG-350A, a tumor-selective anti-CD40 agonist expressing therapeutic, gemcitabine/nab-paclitaxel and ipilimumab for untreated metastatic pancreatic adenocarcinoma: cohort C …

EM O’Reilly, MH O’Hara, G Fisher, RA Wolff, ZA Wainberg, AH Ko, ...

Journal for ImmunoTherapy of Cancer 11 (Suppl 1)

Eileen O'Reilly
2023