Publications

Publications from the sPARK research community. Filter by member authorship or year.

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Genomic analysis of paired primary and metastatic pancreatic ductal adenocarcinoma tumors.

CA McIntyre, V Rudneva, AL Richards, W Park, WR Jarnagin, ...

Journal of Clinical Oncology 43 (4_suppl), 758-758

sPARK LabEileen O'ReillyWungki Park
2025

Health-related quality of life (HRQOL) in the phase 3 trial of cabozantinib vs placebo for advanced neuroendocrine tumors (NET) after progression on prior therapy (CABINET …

AC Dueck, B Fruth, SM Geyer, T Zemla, S Pulsipher, FS Ou, JD Acoba, ...

Journal of Clinical Oncology 43 (16_suppl), 4020-4020

Eileen O'Reilly
2025

Health-related quality of life and performance status with NALIRIFOX versus nab-paclitaxel+ gemcitabine in treatment-naive patients with metastatic pancreatic ductal …

D Melisi, T Macarulla, C De La Fouchardiere, RAP Cid, SR Chandana, ...

ESMO open 10 (8), 105534

Eileen O'Reilly
2025

Hepatic artery infusional chemotherapy for unresectable intrahepatic cholangiocarcinoma

R Alessandris, M Rousian, L Schleimer, H Kalvin, A Cercek, L Connell, ...

HPB 27, S86-S87

Eileen O'Reilly
2025

Impact of clinical target volume utilization on outcomes in patients with non-spine bone oligometastases treated with stereotactic ablative radiation therapy

E O’Reilly, E Johal, H Clark, B Mou, RE Cereno, M Liu, D Schellenberg, ...

Radiotherapy and Oncology 209, 110948

Eileen O'Reilly
2025

Impact of Financial Toxicity on Treatment Adherence and Quality of Life in Pancreatic Cancer

Schleimer LE, Aviki E, Kalvin HL, Magnin J, Sokolowski SS, Kingham TP, O'Reilly EM, Varghese AM, et al.

JCO Oncol Pract

Eileen O'Reilly
2025

Impact of UGT1A1*28 polymorphism on tolerability in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) treated with NALIRIFOX in NAPOLI 3.

M Abdelrahim, G Khan, H Hatoum, A Zervoudakis, F Dayyani, L Zhang, ...

Journal of Clinical Oncology 43 (4_suppl), 717-717

Eileen O'Reilly
2025

Indian Consensus Guidelines for the Management of Pancreatic Cancer

V Lavingia, S Gohel, S Shrikhande, SK Mullapally, A Ramaswamy, ...

Indian Journal of Medical and Paediatric Oncology 46 (05), 435-452

Eileen O'Reilly
2025

Influence of biologic sex and obesity on liver recurrence and survival in patients undergoing upfront surgery for pancreatic adenocarcinoma

Judge SJ, Manin E, Chou J, Torphy RJ, McIntyre CA, Balachandran VP, D'Angelica MI, Drebin JA, et al.

Cancer

sPARK LabWungki ParkEileen O'Reilly
2025

International Fibrolamellar Cancer Registry: Opportunities and Challenges

Al Mahmasani L, Capanu M, Losert K, Chou JF, Lowery MA, Hennessy M, Ray M, Chambers S, et al.

JCO Glob Oncol

Eileen O'Reilly
2025

Intrahepatic Cholangiocarcinoma: Recurrence Patterns, Genomics, and Survival

Chandra P, Song Y, Drill E, Wei AC, Kemeny N, Cercek A, Connell L, Harding J, et al.

JCO Precis Oncol

sPARK LabWungki ParkEileen O'Reilly
2025

Longitudinal imaging markers for pancreas cancer tumor response via Eshelby biomechanics

JS Heiselman, N Horvat, M El Homsi, BL Ecker, EM O’Reilly, TP Kingham, ...

Medical Imaging 2025: Image-Guided Procedures, Robotic Interventions, and …

Eileen O'Reilly
2025

Lymph node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: phase 1 AMPLIFY-201 trial final results

Wainberg ZA, Weekes CD, Furqan M, Kasi PM, Devoe CE, Leal AD, Chung V, Perry JR, et al.

Nat Med

Eileen O'Reilly
2025

Maximal Ablative Irradiation Because of Encasement for Patients with Potentially Resectable Locally Advanced Pancreatic Cancer: Final Results of Phase II MAIBE Trial

M Reyngold, A Wei, C Hajj, M Zinovoy, W Jarnagin, MI D'Angelica, ...

International Journal of Radiation Oncology, Biology, Physics 123 (1), S131-S132

sPARK LabEileen O'ReillyWungki Park
2025

Mitigation of gastrointestinal (GI) side effects among patients receiving NALIRIFOX for metastatic pancreatic ductal adenocarcinoma (mPDAC)

P Patel, A Laursen, C Lieb, F Maxwell, E O'Reilly, AM Siney

Oncology Nursing Forum 52 (2), 426-426

Eileen O'Reilly
2025

Molecular and clinical determinants of targeted therapy (TT) outcomes in biliary tract cancer (BTC): Analysis of a prospectively maintained next generation sequencing (NGS …

D Cowzer, HS Walch, P Atri, F Shah, R Huq, DN Khalil, W Park, R Yeh, ...

Journal of Clinical Oncology 43 (4_suppl), 555-555

sPARK LabEileen O'ReillyWungki Park
2025

MOONRAY-01, a phase 1 study of LY3962673, a potent, orally bioavailable, and selective KRAS G12D inhibitor in KRAS G12D-mutant solid tumors.

NJ Lakhani, D Melisi, V Subbiah, NR Ammakkanavar, EM O'Reilly, ...

Journal of Clinical Oncology 43 (4_suppl), TPS845-TPS845

Eileen O'Reilly
2025

Multi-Institutional Comparison of Ablative 5-Fraction Magnetic Resonance-Guided Online Adaptive Versus 15/25-Fraction Computed Tomography-Guided Moderately Hypofractionated Offline Adapted Radiation Therapy for Locally Advanced Pancreatic Cancer

Chuong MD, O'Reilly EM, Herrera RA, Zinovoy M, Mittauer KE, Rubens M, Kaiser A, Romesser PB, et al.

Cancers (Basel)

Eileen O'Reilly
2025

NAPOLI 3, a phase 3 study of NALIRIFOX in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC): Final overall survival (OS) analysis and characteristics of the …

V Chung, MD Kochenderfer, N Natarajan, GR Williams, AA Laursen, ...

Journal of Clinical Oncology 43 (17_suppl), LBA4175-LBA4175

Eileen O'Reilly
2025

Neratinib alone or in combination with immune checkpoint inhibitors with or without mammalian target of rapamycin inhibitors in patients with fibrolamellar carcinoma

GK Abou-Alfa, T Meyer, RKG Do, SA Piha-Paul, JS Light, S Sherrin, ...

Liver Cancer 14 (1), 58-67

Eileen O'Reilly
2025

Nonoperative Management of Technically Resectable Pancreatic Cancer With Ablative Radiation Therapy

Reyngold M, Schoenfeld JD, O'Reilly EM, Varghese AM, White C, Zinovoy M, Romesser PB, Wu AJ, et al.

JAMA Oncol

sPARK LabWungki ParkEileen O'Reilly
2025

NRG1 fusion-positive solid tumors: clinical detection, genomic landscape, and real-world data in PDAC

AM Schram, SR Yang, M Repetto, R Velasco, G Kahn, R Do, S Dinapoli, ...

Cancer Research 85 (8_Supplement_1), 1151-1151

Eileen O'Reilly
2025

Obesity and biliary tract cancers: Changing epidemiology.

L Al Mahmasani, JF Chou, M Capanu, A Srivastava, CS Sigel, ...

Journal of Clinical Oncology 43 (4_suppl), 643-643

Eileen O'Reilly
2025

OR19-06 Safety and Effectiveness of Sulfonylureas for Pancreas-Cancer Induced Metabolic Dysregulation

JH Flory, H Martirosova, E Tan, M Bakkar, M Goncalves, W Park, ...

Journal of the Endocrine Society 9 (Supplement_1)

sPARK LabEileen O'ReillyWungki Park
2025

Orally administered MOMA-313 as monotherapy or combination therapy in participants with advanced or metastatic solid homologous recombination (HR) deficient tumors: Phase 1 …

A Patnaik, W Abida, KA Reiss, J De Bono, R McKay, AH Bryce, ...

CANCER RESEARCH 85 (8)

Eileen O'Reilly
2025

PASS-01: Randomized Phase II Trial of Modified FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel and Molecular Correlatives for Previously Untreated Metastatic Pancreatic Cancer

Knox JJ, O'Kane G, King D, Laheru D, Habowski AN, Yu K, Perez K, Aguirre AJ, et al.

J Clin Oncol

Eileen O'Reilly
2025

Patient-derived organoids and precision medicine: Insights from the PASS-01 clinical trial in PDAC

AN Habowski, H Patel, C Tsang, L St. Surin, D Plenker, FM Kouassi, ...

Cancer Research 85 (8_Supplement_1), 5998-5998

Eileen O'Reilly
2025

Pembrolizumab and Olaparib (POLAR) Maintenance Therapy in Metastatic Pancreatic Cancer With or Without Homologous Repair Deficiency: A Biomarker Selected Phase II Trial

Park W, O'Connor C, Chou J, Hilmi M, Tarcan Z, Schwartz C, Larsen M, Chatila W, et al.

Res Sq

sPARK LabWungki ParkEileen O'ReillyFiyinfolu BalogunMarc Hilmi
2025

Phase 3 trial of cabozantinib to treat advanced neuroendocrine tumors

JA Chan, S Geyer, T Zemla, MV Knopp, S Behr, S Pulsipher, FS Ou, ...

New England Journal of Medicine 392 (7), 653-665

Eileen O'Reilly
2025

Plant-based diet and survival among patients with metastatic colorectal cancer

E Cheng, FS Ou, C Gatten, C Ma, AP Venook, HJ Lenz, EM O’Reilly, ...

JNCI: Journal of the National Cancer Institute 117 (1), 169-179

Eileen O'Reilly
2025

Prognostic and predictive role of circulating tumor DNA (ctDNA) in stage III colon cancer treated with celecoxib: Findings from CALGB (Alliance)/SWOG 80702.

JA Nowak, Q Shi, T Twombly, LD Pederson, C Ma, JP Vaeyrynen, ...

Journal of Clinical Oncology 43 (4_suppl), LBA14-LBA14

Eileen O'Reilly
2025

Prognostic and predictive role of T cell infiltration in stage III colon cancer (CC) treated with celecoxib: CALGB/SWOG 80702

Y Takashima, C Ma, Q Shi, AD Costa, T Twombly, JP Väyrynen, M Zhao, ...

Cancer Research 85 (8_Supplement_1), 5858-5858

Eileen O'Reilly
2025

Radiomic signatures to estimate survival in patients with advanced hepatocellular carcinoma treated with sorafenib: Cancer and Leukemia Group B 80802 (Alliance)

L Dercle, S Geyer, AB Nixon, F Innocenti, Q Shi, SB Jacobson, L Luk, ...

ESMO open 10 (12), 105848

Eileen O'Reilly
2025

Randomized phase II trial of olaparib+ pembrolizumab vs olaparib alone as maintenance therapy in patients with metastatic pancreatic cancer with germline BRCA1 or BRCA2 …

V Chung, KA Guthrie, MJ Pishvaian, AM Lowy, D Sohal, KA Reiss, ...

Journal of Clinical Oncology 43 (4_suppl), TPS793-TPS793

Eileen O'Reilly
2025

Randomized Phase II Trial of Pazopanib Versus Placebo in Patients With Advanced Extrapancreatic Neuroendocrine Tumors (Alliance A021202)

Bergsland EK, Geyer S, Asmis TR, Behr SC, Kuebler JP, Kumthekar P, Mazza G, Maitland ML, et al.

J Clin Oncol

Eileen O'Reilly
2025

Randomized trial of standard chemotherapy alone or combined with atezolizumab as adjuvant therapy for patients with stage III deficient DNA mismatch repair (dMMR) colon cancer …

FA Sinicrope, FS Ou, D Arnold, W Peters, RJ Behrens, CH Lieu, K Matin, ...

Journal of Clinical Oncology 43 (17_suppl), LBA1-LBA1

Eileen O'Reilly
2025

RNA neoantigen vaccines prime long-lived CD8+ T cells in pancreatic cancer

Sethna Z, Guasp P, Reiche C, Milighetti M, Ceglia N, Patterson E, Lihm J, …

Nature 639(8056), 1042–1051

sPARK LabWungki ParkEileen O'Reilly
2025

Sex differences in chemotherapy completion and adverse events among patients with colon cancer (CALGB/SWOG 80702)(Alliance).

E Cheng, Q Shi, AF Shields, C Kuang, A Shergill, C Ma, KA Guthrie, ...

Journal of Clinical Oncology 43 (16_suppl), 3624-3624

Eileen O'Reilly
2025

Sex differences in chemotherapy completion, toxicities, and survival in colon cancer: an analysis of 2201 patients from CALGB/SWOG 80702 (Alliance)

Cheng E, Shi Q, Shields AF, Xue X, Rohan TE, Kuang C, Shergill AP, Ma C, et al.

J Natl Cancer Inst

Eileen O'Reilly
2025

Survival in Young-Onset Metastatic Colorectal Cancer: Findings From Cancer and Leukemia Group B (Alliance)/SWOG 80405 (vol 114, pg 427, 2021)

M Lipsyc-Sharf, S Zhang, FS Ou, C Ma, NJ McCleary, D Niedzwiecki, ...

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE 117 (7), 1525-1525

Eileen O'Reilly
2025

Survival of patients with resected microsatellite instability-high, mismatch repair deficient, and lynch syndrome-associated pancreatic ductal adenocarcinomas

EL Eikenboom, N Nasar, K Seier, M Gönen, MCW Spaander, EM O’Reilly, ...

Annals of surgical oncology 32 (5), 3568-3577

Eileen O'Reilly
2025

Survival Outcomes and Genetic Characteristics of Resected Pancreatic Acinar Cell Carcinoma

Blair AB, Radomski SN, Chou J, Liu M, Howell TC, Park W, O'Reilly EM, Zheng L, et al.

Ann Surg Oncol

sPARK LabWungki ParkEileen O'Reilly
2025

Target identification for antibody-drug-conjugate (ADC) therapy in biliary tract cancers (BTC)

A Dhyani, Z Tarcan, J Chou, R Thummalapalli, W Chatila, S Nag, E Rosen, ...

Cancer Research 85 (8_Supplement_1), 724-724

sPARK LabEileen O'ReillyWungki Park
2025

The Noncoding Mutational Landscape of Pancreatic Cancer Reveals Recurrent Somatic Mutations in Enhancer Regions

Hayashi A, Ho YJ, Makohon-Moore AP, Zucker A, Hong J, Umeda S, Karnoub ER, Huang J, et al.

Cancer Res Commun

sPARK LabWungki ParkEileen O'Reilly
2025

Trial in progress: RASolute 302—A phase 3, multicenter, global, open-label, randomized study of daraxonrasib (RMC-6236), a RAS (ON) multi-selective inhibitor, versus standard …

BM Wolpin, ZA Wainberg, I Garrido-Laguna, GA Manji, AI Spira, NS Azad, ...

Journal of Clinical Oncology 43 (16_suppl), TPS4230-TPS4230

Eileen O'Reilly
2025

Trials in progress: Alliance A022104/NRG-GI010—A randomized phase II/III trial testing the efficacy of triplet versus doublet chemotherapy regarding clinical complete response …

CS Kitchens, Q Shi, A Dasari, J Garcia-Aguilar, HK Sanoff, TJ George, ...

Journal of Clinical Oncology 43 (16_suppl), TPS3650-TPS3650

Eileen O'Reilly
2025

Tu1375: INCIDENCE OF PANCREATIC ADENOCARCINOMA AND NEOPLASTIC PROGRESSION DURING IMAGING SURVEILLANCE IN HIGH-RISK INDIVIDUALS FOR PANCREATIC CANCER

SE Lee, MA Schattner, J Naduparambil, K O’Connell, N Peeri, P Wang, ...

Gastroenterology 169 (1), S-1411

Eileen O'Reilly
2025

Utilizing Patient Input in Rectal Cancer Trial Design

Alvarez J, Zambare W, George M, Garcia R, Gallagher P, Kitchens C, Bercz A, Kim MJ, et al.

J Natl Cancer Inst

Eileen O'Reilly
2025

1141O Cabozantinib versus placebo for advanced neuroendocrine tumors (NET) after progression on prior therapy (CABINET Trial/Alliance A021602): Updated results including …

J Chan, S Geyer, T Zemla, MV Knopp, SC Behr, S Pulsipher, J Acoba, ...

Annals of Oncology 35, S749

Eileen O'Reilly
2024

1504MO Phase II trial of Pembrolizumab and OLApaRib (POLAR) maintenance for select patients (pts) with metastatic pancreatic cancer (mPC) with (A) homologous recombination …

W Park, C O’Connor, J Chou, C Schwartz, M Larsen, A Varghese, K Yu, ...

Annals of Oncology 35, S922

sPARK LabEileen O'ReillyWungki ParkFiyinfolu Balogun
2024