Publications

Publications from the sPARK research community. Filter by member authorship or year.

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Do pancreatic cancer (PDA) stem cell markers predict biologic behavior?

IH Sahin, M Turkekul, M Capanu, G Askan, B McMahon, KH Yu, ...

Journal of Clinical Oncology 34 (15_suppl), 4112-4112

Eileen O'Reilly
2016

Early Detection and Treatment Opportunities in Pancreatic Adenocarcinoma

EM O’Reilly

Journal of Oncology Practice 12 (1), 31

Eileen O'Reilly
2016

Expression levels of aldehyde dehydrogenase 1A1 (ALDH1A1) in circulating tumor and invasive cells (CTICs) as a biomarker for drug resistance and disulfiram in pancreatic …

M Ricigliano, B Cooper, AJ Ocean, H Tiriac, DA Tuveson, KH Yu, ...

Journal of Clinical Oncology 34 (15_suppl), e15755-e15755

Eileen O'Reilly
2016

Gemcitabine-related pneumonitis in pancreas adenocarcinoma—an infrequent event: elucidation of risk factors and management implications

IH Sahin, AI Geyer, DW Kelly, EM O'Reilly

Clinical colorectal cancer 15 (1), 24-31

Eileen O'Reilly
2016

Genetic diversity of pancreatic ductal adenocarcinoma and opportunities for precision medicine

ES Knudsen, EM O’Reilly, JR Brody, AK Witkiewicz

Gastroenterology 150 (1), 48-63

Eileen O'Reilly
2016

Genomic instability in pancreatic adenocarcinoma: a new step towards precision medicine and novel therapeutic approaches

IH Sahin, MA Lowery, ZK Stadler, E Salo-Mullen, CA Iacobuzio-Donahue, ...

Expert review of gastroenterology & hepatology 10 (8), 893-905

Eileen O'Reilly
2016

Genomic landscape of pancreatic adenocarcinoma: Does age matter?

I Ben-Aharon, M Elkabets, R Pelossof, KH Yu, PJ Allen, ...

Journal of Clinical Oncology 34 (4_suppl), 250-250

Eileen O'Reilly
2016

Genomic profiling of pancreas ductal adenocarcinoma (PDA), actionability, and correlation with clinical phenotype.

E Jordan, MA Lowery, R Ptashkin, A Zehir, MF Berger, H Maynard, ...

Journal of Clinical Oncology 34 (15_suppl), 4127-4127

Eileen O'Reilly
2016

Identification of potentially actionable molecular alterations in advanced hepatocellular carcinoma (HCC).

JJ Harding, ZJ Heins, LC Connell, T Soumerai, NE Kemeny, WR Jarnagin, ...

Journal of Clinical Oncology 34 (15_suppl), e15635-e15635

Eileen O'Reilly
2016

Impact of primary (1º) tumor location on overall survival (OS) and progression-free survival (PFS) in patients (pts) with metastatic colorectal cancer (mCRC): Analysis of CALGB …

AP Venook, D Niedzwiecki, F Innocenti, B Fruth, C Greene, BH O'Neil, ...

Journal of Clinical Oncology 34 (15_suppl), 3504-3504

Eileen O'Reilly
2016

Integrated patient-derived models delineate individualized therapeutic vulnerabilities of pancreatic cancer

AK Witkiewicz, U Balaji, C Eslinger, E McMillan, W Conway, B Posner, ...

Cell reports 16 (7), 2017-2031

Eileen O'Reilly
2016

Intensity modulated radiation therapy reduces gastrointestinal toxicity in locally advanced pancreas cancer

S Prasad, L Cambridge, F Huguet, JF Chou, Z Zhang, AJ Wu, EM O’Reilly, ...

Practical radiation oncology 6 (2), 78-85

Eileen O'Reilly
2016

Is it time to split strategies to treat homologous recombinant deficiency in pancreas cancer?

MY Teo, EM O’Reilly

Journal of gastrointestinal oncology 7 (5), 738

Eileen O'Reilly
2016

Management of metastatic pancreatic adenocarcinoma

AR Cheema, EM O’Reilly

Surgical Clinics 96 (6), 1391-1414

Eileen O'Reilly
2016

Metastatic pancreatic cancer: American Society of Clinical Oncology clinical practice guideline

DPS Sohal, PB Mangu, AA Khorana, MA Shah, PA Philip, EM O’Reilly, ...

Journal of Clinical Oncology 34 (23), 2784-2796

Eileen O'Reilly
2016

Molecular signature of pancreatic adenocarcinoma: an insight from genotype to phenotype and challenges for targeted therapy

IH Sahin, CA Iacobuzio-Donahue, EM O’Reilly

Expert opinion on therapeutic targets 20 (3), 341-359

Eileen O'Reilly
2016

Oxaliplatin neurotoxicity has a spectrum of manifestations from an often reversible acute neurotoxicity to a more irreversible “stocking and glove” chronic neuropathy that is …

IH Sahin, AI Geyer, DW Kelly, EM O'Reilly

Clinical Colorectal Cancer 15 (1), 37-46

Eileen O'Reilly
2016

Pancreas adenocarcinoma: ascites, clinical manifestations, and management implications

AM Hicks, J Chou, M Capanu, MA Lowery, KH Yu, EM O'Reilly

Clinical colorectal cancer 15 (4), 360-368

Eileen O'Reilly
2016

Patient-reported outcomes of a multicenter phase 2 study investigating gemcitabine and stereotactic body radiation therapy in locally advanced pancreatic cancer

AD Rao, EA Sugar, DT Chang, KA Goodman, A Hacker-Prietz, LM Rosati, ...

Practical radiation oncology 6 (6), 417-424

Eileen O'Reilly
2016

Phase 1B trial of ADI-PEG 20 (A) plus nab-Paclitaxel (nab-P) and gemcitabine (gem) in subjects with advanced pancreatic cancer (APC).

MA Lowery, M Capanu, DC Glassman, CM Covington, J Gluskin, ...

Journal of Clinical Oncology 34 (15_suppl), e15756-e15756

Eileen O'Reilly
2016

Phase I trial of HuMab-5B1 (MVT-5873), a novel monoclonal antibody targeting sLea, in patients with advanced pancreatic cancer and other CA19-9 positive malignancies

EM O'Reilly, TM Bauer, J Infante, JC Gutheil, P Klein, KH Yu, MA Lowery, ...

Proceedings of the American Association of Cancer Researchers 57

Eileen O'Reilly
2016

Presentation, clinical behavior, outcomes and therapies for patients with advanced pancreas adenocarcinoma (PAC) who present with or develop ascites.

A Mier Hicks, EM O'Reilly, M Capanu, MA Lowery, KH Yu

Journal of Clinical Oncology 34 (4_suppl), 209-209

Eileen O'Reilly
2016

ReCAP: hospitalizations in older adults with advanced cancer: the role of chemotherapy

CB O’Neill, CL Atoria, EM O’Reilly, MC Henman, PB Bach, EB Elkin, ...

Journal of oncology practice 12 (2), 151-152

Eileen O'Reilly
2016

Safety, pharmacokinetics, pharmacodynamics, and antitumor activity of necuparanib combined with nab-paclitaxel and gemcitabine in patients with metastatic pancreatic cancer …

EM O'Reilly, D Mahalingam, JM Roach, PJ Miller, ME Rosano, S Krause, ...

Journal of Clinical Oncology 34 (15_suppl), 4117-4117

Eileen O'Reilly
2016

Second-line chemotherapy (CTx) outcomes in advanced biliary cancers (ABC): A retrospective multicenter analysis.

MA Lowery, LW Goff, E Jordan, R Wang, AG Bocobo, JF Chou, ...

Journal of Clinical Oncology 34 (4_suppl), 437-437

Eileen O'Reilly
2016

Second-line chemotherapy (CTx) outcomes in advanced biliary cancers (ABC): A retrospective multicenter analysis.

LW Goff, MA Lowery, E Jordan, R Wang, AG Bocobo, JF Chou, ...

Journal of Clinical Oncology 34 (15_suppl), e15636-e15636

Eileen O'Reilly
2016

Texture analysis for survival prediction of pancreatic ductal adenocarcinoma patients with neoadjuvant chemotherapy

J Chakraborty, L Langdon-Embry, JG Escalon, PJ Allen, MA Lowery, ...

Medical Imaging 2016: Image Processing 9784, 505-510

Eileen O'Reilly
2016

Weight loss, diabetes, fatigue, and depression preceding pancreatic cancer

SH Olson, Y Xu, K Herzog, A Saldia, EM DeFilippis, P Li, PJ Allen, ...

Pancreas 45 (7), 986

Eileen O'Reilly
2016

Well-differentiated neuroendocrine tumors with a morphologically apparent high-grade component: a pathway distinct from poorly differentiated neuroendocrine carcinomas

LH Tang, BR Untch, DL Reidy, E O'Reilly, D Dhall, L Jih, O Basturk, ...

Clinical Cancer Research 22 (4), 1011-1017

Eileen O'Reilly
2016

Well-differentiated neuroendocrine tumors with a morphologically apparent high-grade component: a pathway distinct from poorly differentiated neuroendocrine carcinomas (vol 22 …

LH Tang, BR Untch, DL Reidy, E O'Reilly, D Dhall, L Jih

CLINICAL CANCER RESEARCH 22 (16), 4273-4273

Eileen O'Reilly
2016

‘We have to discuss it’: cancer patients' advance care planning impressions following educational information about cardiopulmonary resuscitation

AS Epstein, E Shuk, EM O'reilly, KA Gary, AE Volandes

Psycho‐Oncology 24 (12), 1767-1773

Eileen O'Reilly
2015

“Months, not years”: Impact of clinical discussions of advanced cancer life-expectancy on patient illness understanding.

AS Epstein, HG Prigerson, L Saltz, EM O'Reilly, MA Shah, PK Maciejewski

Journal of Clinical Oncology 33 (15_suppl), 9549-9549

Eileen O'Reilly
2015

“This is not me”: patient, family, cultural and clinician considerations in cases of severe cancer-related debility

D Li, GK Abou-Alfa, AD Viny, M Cammarata, A Shamseddine, A Al-Olayan, ...

Journal of Gastrointestinal Oncology 6 (5), 589

Eileen O'Reilly
2015

90Y-clivatuzumab tetraxetan with or without low-dose gemcitabine: A phase Ib study in patients with metastatic pancreatic cancer after two or more prior therapies

VJ Picozzi, RK Ramanathan, MA Lowery, AJ Ocean, EP Mitchel, ...

European Journal of Cancer 51 (14), 1857-1864

Eileen O'Reilly
2015

A phase I trial of binimetinib in combination with gemcitabine (G) and cisplatin (C) patients (pts) with untreated advanced biliary cancer (ABC).

MA Lowery, EM O'Reilly, JJ Harding, E Salehi, E Hollywood, M Bradley, ...

Journal of Clinical Oncology 33 (15_suppl), e15125-e15125

Eileen O'Reilly
2015

Abstract B98: Final results of a randomized phase Ib study of fractionated 90Y-clivatuzumab tetraxetan in patients with metastatic pancreatic cancer having at least two prior …

VJ Picozzi, RK Ramanathan, MA Lowery, AJ Ocean, EP Mitchell, ...

Cancer Research 75 (13_Supplement), B98-B98

Eileen O'Reilly
2015

Abstract IA28: BRCA-mutated pancreas adenocarcinoma: Emerging therapeutic implications

EM O'Reilly

Cancer Research 75 (13_Supplement), IA28-IA28

Eileen O'Reilly
2015

Adjuvant and neoadjuvant systemic therapy for pancreas adenocarcinoma

D Li, EM O’Reilly

Seminars in oncology 42 (1), 134-143

Eileen O'Reilly
2015

Coagulation factors in citrated plasma predict for benefit from bevacizumab (B) in patients with advanced pancreatic cancer (APC): Results from CALGB 80303 (Alliance).

JM Clarke, H Pang, MD Starr, AJ Hatch, HL Kindler, EM O'Reilly, ...

Journal of Clinical Oncology 33 (3_suppl), 306-306

Eileen O'Reilly
2015

EBV-associated lymphoepithelioma-like carcinoma of the pancreas: case report with targeted sequencing analysis

RT Samdani, JF Hechtman, E O'Reilly, R DeMatteo, CS Sigel

Pancreatology 15 (3), 302-304

Eileen O'Reilly
2015

Final results of a randomized phase Ib study of fractionated 90Y-clivatuzumab tetraxetan in patients with metastatic pancreatic cancer having at least two prior therapies

VJ Picozzi, RK Ramanathan, MA Lowery, AJ Ocean, EP Mitchell, ...

CANCER RESEARCH 75

Eileen O'Reilly
2015

Final results of phase Ib of anticancer stem cell antibody tarextumab (OMP-59R5, TRXT, anti-Notch 2/3) in combination with nab-paclitaxel and gemcitabine (Nab-P+ Gem) in …

EM O'Reilly, LS Smith, JC Bendell, JH Strickler, M Zalupski, W Gluck, ...

Journal of Clinical Oncology 33 (3_suppl), 278-278

Eileen O'Reilly
2015

FOLFIRINOX induction therapy for stage 3 pancreatic adenocarcinoma

E Sadot, A Doussot, EM O’Reilly, MA Lowery, KA Goodman, RKG Do, ...

Annals of surgical oncology 22 (11), 3512-3521

Eileen O'Reilly
2015

Hepatocellular carcinoma (HCC) and bone metastases (Mets).

JJ Harding, G Abu Zeinah, JF Chou, DH Owen, M Ly, MA Lowery, ...

Journal of Clinical Oncology 33 (15_suppl), e15129-e15129

Eileen O'Reilly
2015

Identification of germline genetic mutations in patients with pancreatic cancer

EE Salo‐Mullen, EM O'Reilly, DP Kelsen, AM Ashraf, MA Lowery, KH Yu, ...

Cancer 121 (24), 4382-4388

Eileen O'Reilly
2015

Intensity-modulated radiation therapy (IMRT) in patients with locally advanced pancreatic cancer (LAPC).

C Hajj, F Huguet, AJC Wu, EM O'Reilly, C Winston, DL Reidy, PJ Allen, ...

Journal of Clinical Oncology 33 (3_suppl), 377-377

Eileen O'Reilly
2015

Intrahepatic cholangiocarcinoma: expert consensus statement

SM Weber, D Ribero, EM O'Reilly, N Kokudo, M Miyazaki, TM Pawlik

Hpb 17 (8), 669-680

Eileen O'Reilly
2015

JANUS 2: A phase III study of survival, tumor response, and symptom response with ruxolitinib plus capecitabine or placebo plus capecitabine in patients with advanced or …

EM O'Reilly, C Walker, J Clark, KJ Brill, FW Dawkins, JC Bendell

Journal of Clinical Oncology 33 (15_suppl), TPS4146-TPS4146

Eileen O'Reilly
2015

Liver resection for metastatic colorectal leiomyosarcoma: a single center experience

W Faraj, J El-Kehdy, G El Nounou, S Deeba, H Fakih, M Jabbour, ...

Journal of gastrointestinal oncology 6 (5), E70

Eileen O'Reilly
2015

Liver-directed conversion therapy in metastatic colon cancer

A Snyder, N Kemeny, A Shamseddine, A Al-Olayan, F El-Merhi, ...

Journal of Gastrointestinal Oncology 6 (3), 322

Eileen O'Reilly
2015