Publications

Publications from the sPARK research community. Filter by member authorship or year.

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Combining tumor deposits with the number of lymph node metastases to improve the prognostic accuracy in stage III colon cancer: a post hoc analysis of the CALGB/SWOG 80702 …

R Cohen, Q Shi, J Meyers, Z Jin, M Svrcek, C Fuchs, F Couture, P Kuebler, ...

Annals of Oncology 32 (10), 1267-1275

Eileen O'Reilly
2021

Dietary fat in relation to overall and progression-free survival among patients (pts) with advanced or metastatic colorectal cancer (CRC): Data from CALGB 80405 (Alliance).

E Van Blarigan, C Ma, FS Ou, AP Venook, K Ng, D Niedzwiecki, ...

Journal of Clinical Oncology 39 (15_suppl), 3588-3588

Eileen O'Reilly
2021

Discordance between central versus local response assessments in neuroendocrine tumor (NET) patients (pts) enrolled in A021202.

SM Geyer, MR Mahoney, TR Asmis, N Hall, S Karovic, MV Knopp, ...

Journal of Clinical Oncology 39 (3_suppl), 361-361

Eileen O'Reilly
2021

Early-onset pancreas cancer: clinical descriptors, genomics, and outcomes

Varghese AM, Singh I, Singh R, Kunte S, Chou JF, Capanu M, Wong W, … Park W, …

JNCI: Journal of the National Cancer Institute 113(9), 1194–1202

sPARK LabWungki ParkEileen O'Reilly
2021

Effect of celecoxib vs placebo added to standard adjuvant therapy on disease-free survival among patients with stage III colon cancer: the CALGB/SWOG 80702 (Alliance …

JA Meyerhardt, Q Shi, CS Fuchs, J Meyer, D Niedzwiecki, T Zemla, ...

Jama 325 (13), 1277-1285

Eileen O'Reilly
2021

Efficacy and safety of zenocutuzumab in advanced pancreatic cancer and other solid tumors harboring NRG1 fusions

AM Schram, E O’Reilly, G O’Kane

J Clin Oncol 39 (15), 3003

Eileen O'Reilly
2021

Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS

Rose Brannon A, Jayakumaran G, Diosdado M, Patel J, Razumova A, Hu Y, Meng F, Haque M, et al.

Nat Commun

Eileen O'Reilly
2021

Evaluation of neratinib (N), pembrolizumab (P), everolimus (E), and nivolumab (V) in patients (pts) with fibrolamellar carcinoma (FLC).

GK Abou-Alfa, T Meyer, J Zhang, S Sherrin, A Yaqubie, A Clemens O’Neill, ...

Journal of Clinical Oncology 39 (3_suppl), 310-310

Eileen O'Reilly
2021

Gemcitabine (Gem) and nab-paclitaxel (NP)±nivolumab (nivo)±CD40 agonistic monoclonal antibody APX005M (sotigalimab), in patients (Pts) with untreated metastatic pancreatic …

MH O'Hara, EM O'Reilly, RA Wolff, ZA Wainberg, AH Ko, OE Rahma, ...

Journal of Clinical Oncology 39 (15_suppl), 4019-4019

Eileen O'Reilly
2021

IGF-binding proteins, adiponectin, and survival in metastatic colorectal cancer: results from CALGB (Alliance)/SWOG 80405

BJ Guercio, S Zhang, FS Ou, AP Venook, D Niedzwiecki, HJ Lenz, ...

JNCI Cancer Spectrum 5 (1), pkaa074

Eileen O'Reilly
2021

Immune Landscape of Pancreas Ductal Adenocarcinoma: Current Therapeutic Strategies and Future Perspective

B Zheng-Lin, EM O’Reilly

Immune Strategies for Gastrointestinal Cancer, 221-255

Eileen O'Reilly
2021

Improving outcomes and shared decisions in pancreatic cancer using animated pancreas patient (APP) visual formats of learning: A National Pancreas Foundation (NPF) patient …

S Munigala, EM O'Reilly, M Alsante, J Holt, AH Ko, A Gelrud

Journal of Clinical Oncology 39 (15_suppl), e16242-e16242

Eileen O'Reilly
2021

Influence of dietary insulin scores on survival in patients with metastatic colorectal cancer (mCRC): Findings from CALGB (Alliance) 80405.

K DiNardo, C Ma, FS Ou, C Yuan, BJ Guercio, V Morales-Oyarvide, ...

Journal of Clinical Oncology 39 (15_suppl), 3568-3568

Eileen O'Reilly
2021

LBA-1 Phase 3 APACT trial of adjuvant nab-paclitaxel plus gemcitabine (nab-P+ Gem) vs gemcitabine (Gem) alone in patients with resected pancreatic cancer (PC): updated 5-year …

M Tempero, E O'Reilly, E Van Cutsem, J Berlin, P Philip, D Goldstein, ...

Annals of Oncology 32, S226

Eileen O'Reilly
2021

Leptomeningeal disease in pancreas ductal adenocarcinoma: A manifestation of longevity

O'Connor CA, Park JS, Kaley T, Kezlarian B, Edelweiss M, Yang TJ, Park W, Reidy D, et al.

Pancreatology

sPARK LabWungki ParkEileen O'Reilly
2021

Local Control and Survival After Induction Chemotherapy and Ablative Radiation Versus Resection for Pancreatic Ductal Adenocarcinoma With Vascular Involvement

Jolissaint JS, Reyngold M, Bassmann J, Seier KP, Gönen M, Varghese AM, Yu KH, Park W, et al.

Ann Surg

sPARK LabWungki ParkEileen O'Reilly
2021

MO31-6 Maintenance olaparib in Asian patients with germline BRCA-mutated metastatic pancreatic cancer

DY Oh, JO Park, HL Kindler, P Hammel, M Reni, E Van Cutsem, ...

Annals of Oncology 32, S319

Eileen O'Reilly
2021

Multimodality therapy in metastatic pancreas cancer with a BRCA mutation and durable long-term outcome: biology, intervention, or both?

TL Sutton, A Grossberg, F Ey, EM O’Reilly, BC Sheppard

Cancer Biology & Therapy 22 (10-12), 532-536

Eileen O'Reilly
2021

MULTIOMIC BIOMARKER SIGNATURES IDENTIFY SUBSETS OF PATIENTS WHO MAY BENEFIT FROM EITHER NIVOLUMAB OR SOTIGALIMAB IN COMBINATION WITH CHEMOTHERAPY IN METASTATIC PANCREATIC CANCER

D Maurer, JX Yu, K Sklodowski, M Tognetti, L Reiter, R Bruderer, ...

JOURNAL FOR IMMUNOTHERAPY OF CANCER 9, A370-A370

Eileen O'Reilly
2021

Myelodysplastic syndrome and acute myeloid leukaemia in patients treated with PARP inhibitors: a safety meta-analysis of randomised controlled trials and a retrospective study …

PM Morice, A Leary, C Dolladille, B Chrétien, L Poulain, ...

The Lancet Haematology 8 (2), e122-e134

Eileen O'Reilly
2021

Noninvasive detection of polyclonal acquired resistance to FGFR inhibition in patients with cholangiocarcinoma harboring FGFR2 alterations

AM Varghese, J Patel, YY Janjigian, F Meng, SD Selcuklu, G Iyer, ...

JCO Precision Oncology 5, 44-50

Eileen O'Reilly
2021

Overall survival from the phase 3 POLO trial: Maintenance olaparib for germline BRCA-mutated metastatic pancreatic cancer.

T Golan, P Hammel, M Reni, E Van Cutsem, T Macarulla, MJ Hall, ...

Journal of Clinical Oncology 39 (3_suppl), 378-378

Eileen O'Reilly
2021

P86. 08 phase 2 study of zenocutuzumab (MCLA-128), a bispecific HER2/HER3 antibody in NRG1 fusion-positive advanced solid tumors

A Schram, T Macarulla, E O’Reilly, J Rodon, B Wolpin, S Ou, D Kim, ...

Journal of Thoracic Oncology 16 (3), S675

Eileen O'Reilly
2021

Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes

Momtaz P, O'Connor CA, Chou JF, Capanu M, Park W, Bandlamudi C, Berger MF, Kelsen DP, et al.

Cancer

sPARK LabWungki ParkEileen O'Reilly
2021

Pancreas cancer: Therapeutic trials in metastatic disease

Smithy JW, O'Reilly EM

J Surg Oncol

Eileen O'Reilly
2021

Pancreatic cancer stem cells may define tumor stroma characteristics and recurrence patterns in pancreatic ductal adenocarcinoma

Askan G, Sahin IH, Chou JF, Yavas A, Capanu M, Iacobuzio-Donahue CA, Basturk O, O'Reilly EM

BMC Cancer

Eileen O'Reilly
2021

Pancreatic cancer: a review

Park W, Chawla A, O'Reilly EM

JAMA 326(9), 851–862

sPARK LabWungki ParkEileen O'Reilly
2021

Pancreatic cancer: a review (vol 326, pg 851, 2021)

W Park, A Chawla, EM O'Reilly

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION 326 (20), 2081-2081

sPARK LabEileen O'ReillyWungki Park
2021

Persistent disparities in treatment and survival for patients with pancreatic cancer despite insurance expansion policies

LV Saadat, JF Chou, M Gonen, KC Soares, VP Balachandran, ...

HPB 23, S624

Eileen O'Reilly
2021

Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

Joshi S, Gomes ED, Wang T, Corben A, Taldone T, Gandu S, Xu C, Sharma S, et al.

Commun Biol

Eileen O'Reilly
2021

POLO: Radiologic assessment of the impact of maintenance olaparib in patients (pts) with metastatic pancreatic cancer (mPaC).

LH Schwartz, HL Kindler, P Hammel, M Reni, E Van Cutsem, T Macarulla, ...

Journal of Clinical Oncology 39 (3_suppl), 412-412

Eileen O'Reilly
2021

POLO: subsequent therapy after maintenance olaparib in patients with a germline BRCA mutation and metastatic pancreatic cancer

D Arnold, T Golan, P Hammel, M Reni, E Van Cutsem, T Macarulla, ...

Oncology Research And Treatment 44, 221-221

Eileen O'Reilly
2021

Preoperative CT predictors of survival in patients with pancreatic ductal adenocarcinoma undergoing curative intent surgery

SM Dickinson, CA McIntyre, JB Schilsky, KA Harrington, SR Gerst, ...

Abdominal Radiology 46 (4), 1607-1617

Eileen O'Reilly
2021

Prognostic value of the Memorial Sloan Kettering Prognostic Score in metastatic pancreatic adenocarcinoma

Lebenthal JM, Zheng J, Glare PA, O'Reilly EM, Yang AC, Epstein AS

Cancer

Eileen O'Reilly
2021

Prognostic value of tumor deposits in stage III colon cancer patients, a post-hoc analysis of CALGB/SWOG 80702 phase III study.

R Cohen, Q Shi, JP Meyers, Z Jin, M Svrcek, CS Fuchs, F Couture, ...

Journal of Clinical Oncology 39 (3_suppl), 10-10

Eileen O'Reilly
2021

Radiomic signatures to predict survival in patients with advanced hepatocellular carcinoma (HCC) treated with sorafenib+/-doxorubicin: Correlative science from CALGB 80802 …

L Dercle, SM Geyer, AB Nixon, F Innocenti, Q Shi, SB Jacobson, L Luk, ...

Journal of Clinical Oncology 39 (3_suppl), 343-343

Eileen O'Reilly
2021

Randomized Phase II Study of PET Response-Adapted Combined Modality Therapy for Esophageal Cancer: Mature Results of the CALGB 80803 (Alliance) Trial

Goodman KA, Ou FS, Hall NC, Bekaii-Saab T, Fruth B, Twohy E, Meyers MO, Boffa DJ, et al.

J Clin Oncol

Eileen O'Reilly
2021

Randomized phase II trial of olaparib+ pembrolizumab versus olaparib alone as maintenance therapy in metastatic pancreatic cancer patients with germline BRCA1 or BRCA2 (g BRCA …

V Chung, KA Guthrie, MJ Pishvaian, AM Lowy, EG Chiorean, MT Duong, ...

Journal of Clinical Oncology 39 (3_suppl), TPS447-TPS447

Eileen O'Reilly
2021

Real-world overall survival of patients diagnosed with recurrent versus de novo metastatic pancreatic ductal adenocarcinoma (PDAC).

EM O'Reilly, KH Yu, N Lamarre, A Surinach, P Cockrum

Journal of Clinical Oncology 39 (15_suppl), e16250-e16250

Eileen O'Reilly
2021

Retrospective Case Series Analysis of RAF Family Alterations in Pancreatic Cancer: Real-World Outcomes From Targeted and Standard Therapies

A Hendifar, EM Blais, B Wolpin, V Subbiah, E Collisson, I Singh, ...

JCO Precision Oncology 5, 1325-1338

Eileen O'Reilly
2021

Targeting DNA Damage Repair Mechanisms in Pancreas Cancer

Perkhofer L, Golan T, Cuyle PJ, Matysiak-Budnik T, Van Laethem JL, Macarulla T, Cauchin E, Kleger A, et al.

Cancers (Basel)

Eileen O'Reilly
2021

Targeting DNA damage repair pathways in pancreas cancer

Crowley F, Park W, O'Reilly EM

Cancer Metastasis Rev

sPARK LabWungki ParkEileen O'Reilly
2021

Therapeutic Implications of Germline Testing in Patients With Advanced Cancers

Stadler ZK, Maio A, Chakravarty D, Kemel Y, Sheehan M, Salo-Mullen E, Tkachuk K, Fong CJ, et al.

J Clin Oncol

Eileen O'Reilly
2021

Treatment patterns and survival in patients with early-onset pancreatic cancer

Saadat LV, Chou JF, Gonen M, Soares KC, Kingham TP, Varghese AM, Jarnagin WR, D'Angelica MI, et al.

Cancer

Eileen O'Reilly
2021

1527P Assessing clinical benefit of olaparib maintenance treatment in subgroups of patients with germline BRCA mutation (gBRCAm) and metastatic pancreatic cancer: Phase III …

D Hochhauser, H Kindler, P Hammel, M Reni, E Van Cutsem, T Macarulla, ...

Annals of Oncology 31, S940-S941

Eileen O'Reilly
2020

A mixed methods analysis of patients’ advance care planning values in outpatient oncology: Person-Centered Oncologic Care and Choices (P-COCC)

R Agarwal, E Shuk, D Romano, M Genoff, Y Li, EM O’Reilly, W Breitbart, ...

Supportive Care in Cancer 28 (3), 1109-1119

Eileen O'Reilly
2020

A multicenter randomized three‐arm phase II study of (1) everolimus,(2) estrogen deprivation therapy (EDT) with leuprolide+ letrozole, and (3) everolimus+ EDT in patients with …

I El Dika, RJ Mayer, AP Venook, M Capanu, MP LaQuaglia, R Kobos, ...

The oncologist 25 (11), 925-e1603

Eileen O'Reilly
2020

A phase I study to evaluate the safety and tolerability of AB680 combination therapy in participants with gastrointestinal malignancies.

JC Bendell, GA Manji, S Pant, DW Lai, J Colabella, W Berry, MC Paoloni, ...

Journal of Clinical Oncology 38 (4_suppl), TPS788-TPS788

Eileen O'Reilly
2020

A phase I/II study of GB1275, a first-in-class oral CD11b modulator, alone, and combined with pembrolizumab in specified advanced solid tumors or with chemotherapy in …

DW Rasco, JC Bendell, A Wang-Gillam, W Park, EM O'Reilly, L Zhou, ...

Journal of Clinical Oncology 38 (15_suppl), 3085-3085

sPARK LabEileen O'ReillyWungki Park
2020

A phase II basket study of MCLA-128, a bispecific antibody targeting the HER3 pathway, in NRG1 fusion-positive advanced solid tumors

AM Schram, AE Drilon, T Macarulla, EM O'Reilly, J Rodon, BM Wolpin, ...

J Clin Oncol 38 (15_suppl), TPS3654-TPS3654

Eileen O'Reilly
2020